Purpose The aim of the present prospective study was to investigate the efficacy of hyaluronan (HA) using two different concentrations as embryo transfer media for in vitro fertilization embryo transfer cycles. Methods A total of 169 cycles undergoing fresh embryo transfer on day 2 or 3, 561 cycles undergoing frozen-thawed embryo transfer on day 2 or 3, and 484 cycles of frozen-thawed blastoc...

N umerous publications have investigated the practice of elective single-embryo transfer (eSET) (1–27). Single-embryo transfer after in vitro fertilization (IVF) has been advocated as the only effective means to avoid multiple pregnancy in IVF cycles (28). Elective SET is defined as the transfer of a single embryo at either the cleavage or blastocyst stage of embryo development that is selected...

STUDY QUESTION Do number of cells in the transferred cleavage stage embryo and number of oocytes retrieved for IVF influence maternal hCG concentrations in early pregnancies? SUMMARY ANSWER Compared with transfer of a 2-cell embryo, transfer of a 4-cell embryo results in higher hCG concentrations on Day 12 after transfer, and more than 20 oocytes retrieved were associated with low hCG concent...

BACKGROUND New techniques in assessing oocytes and embryo quality are currently explored to improve pregnancy and delivery rates per embryo transfer. While a better understanding of embryo quality could help optimize the existing "in vitro fertilization" (IVF) therapy schemes, it is essential to address the economic viability of such technologies in the healthcare setting. METHODS An Embryo-D...

Development disorders may be arisen from the unavoidable maternal exposure to particulate air pollution during the prenatal life that can be affected not only periconceptional period but also postnatal life. A kind of chemical material categorized as air pollutants are present in the urine, blood and semen of exposed men and may decline sperm count and affect sperm quality. Environment toxic ca...

Our purpose is to explore whether anti-dsDNA antibody, which was demonstrated to enter living cells and induced apoptosis, could adversely affect reproductive outcomes. A total of 259 women receiving the in vitro fertilization-embryo transfer (IVF) cycle were enrolled in this study, including 52 women with positive ANA and anti-dsDNA (ANA+/anti-dsDNA+ group), 86 women with positive ANA and nega...

STUDY QUESTION How long is the individualized training and the stability of competence for the embryo transfer (ET) technique? SUMMARY ANSWER The embryo transfer technique is easy-to-learn, hardly unlearned, and training should be individualized by monitoring with learning curve-cumulative summation (LC-CUSUM) curves. WHAT IS KNOWN ALREADY Like many medical procedures, embryo transfer is an...

The aim of this study was to find the factors explaining the probability of success of in-vitro fertilization (IVF)-embryo transfer and its different stages: stimulation, fertilization and implantation. The sample came from a retrospective cohort followed in the IVF-embryo transfer centre of the Centre Hospitalier Universitaire of Pellegrin, Bordeaux, France; the data from 471 couples giving ri...

Background: The beneficial effect of supplementing culture medium with melatonin has been reported during in vitro embryo development of species such as mouse, bovine and porcine. However, the effect of melatonin on the mouse somatic cell nuclear transfer remained unknown. Materials and Methods: In this study, we assessed the effects of various concentrations of melatonin (10-6 to 10-12 M) on t...

BACKGROUND Single blastocyst transfer has the advantage of maximizing the fresh single pregnancy rate. However, in patients with a low number of good quality embryos on day 3, it remains unclear whether immediate embryo transfer or further embryo culture with blastocyst transfer is the most preferable option. METHODS A retrospective cohort study was carried out in which the outcome of 590 fre...