Modern immunochemical engineering allows the creation of cells that either secrete antibodies or incorporate them into various cellular compartments, including the plasma membrane. Because the receptors for most viruses are known, if one can achieve the proper stoichiometry and geometry, plasma membrane-associated antibodies to these receptors should block viral infection. In this report, we te...

This paper reports dissociation constants and "effective molarities" (M(eff)) for the intramolecular binding of a ligand covalently attached to the surface of a protein by oligo(ethylene glycol) (EG(n)) linkers of different lengths (n = 0, 2, 5, 10, and 20) and compares these experimental values with theoretical estimates from polymer theory. As expected, the value of M(eff) is lowest when the ...

In this work we fabricate and characterize field-effect transistors based on the solution-processable semiconducting polymer poly(3-hexylthiophene) (P3HT). Applying two independent gate potentials to the electrolyte-gated organic field-effect transistor (EGOFET), by using a conventional SiO(2) layer as the back-gate dielectric and the electrolyte-gate as the top-gate, allows the measurement of ...

BACKGROUND Many previous studies show that cell surface sialylation of malignant cells is enhanced compared to normal tissue. The carboxyl group of the sialic acid yields, a negative surface charge of the tumor cells. This study investigates how tumor cell growth is affected when a cationic polymer is incubated with six different tumor cell lines. MATERIALS AND METHODS Cationic dextran (CatDe...

Abstract While natural resources are becoming scarce and climate change is accelerating, the recovery recycling of wastes by-products an effective way to deal with economic ecological constraints recent decades. The valorization industrial in civil engineering a common practice either by their incorporation during manufacture Portland cements or as partial replacement cement production concrete...

Astringency and sourness of lactic, acetic and citric acids, each adjusted to pH 3, 5 and 7, were evaluated in two experiments, one starting at equal concentrations in wt/vol before neutralization and the second starting at equal molarity. Astringency and sourness decreased with increasing pH. However, acids were differentially sour at equal pH, consistent with previous findings. In contrast, t...

We present a new method for analyzing ion, or molecule, distributions around helical nucleic acids and illustrate the approach by analyzing data derived from molecular dynamics simulations. The analysis is based on the use of curvilinear helicoidal coordinates and leads to highly localized ion densities compared to those obtained by simply superposing molecular dynamics snapshots in Cartesian s...

The relationship between molecules having granulocyte colony-stimulating activity (G-CSA), erythroid burst-promoting activity (E-BPA), and activity promoting increase in the number of granulocytic progenitors in liquid culture ( GPA) was explored in conditioned medium from human leukocytes (HLCM) and human placenta (HPCM). As tested on human hemopoietic progenitors in culture. G-CSA eluted from...

In the current study, effect of SiO 2 /Na O ratio in Sodium silicate (Na 3 ) solution, Na /NaOH and molarity NaOH on compressive strength geopolymer concrete. A mix design is formulated with various mixes are casted alkali activator solution (AAS) / fly ash (FA) =0.5 constant content. The molar altered from 1.50 to 3.00 for different ratios (2.0, 2.5 3.0) also molarities (8M,10M,12M,14M,16M 18M...