نتایج جستجو برای: molecular subtypes

تعداد نتایج: 668175  

2014
Jing Chen Peng Jiang Han-jin Wang Jia-yi Zhang Yang Xu Mu-hong Guo Bin Zhang Chong-yin Tang Hong-yong Cao Shui Wang

BACKGROUND Recent research displays that breast cancer (BC) is a heterogeneous disease and distinct molecular subtypes yield different prognostic outcomes. METHODS We conducted a meta-analysis to clarify the role of molecular subtypes in recurrence risk after breast-conserving therapy (BCT). Eligible studies of single- (ER, PR, Her-2, and p53) and triple-molecular (Luminal A, Luminal B, Her-2...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Richard W Tothill Anna V Tinker Joshy George Robert Brown Stephen B Fox Stephen Lade Daryl S Johnson Melanie K Trivett Dariush Etemadmoghadam Bianca Locandro Nadia Traficante Sian Fereday Jillian A Hung Yoke-Eng Chiew Izhak Haviv Dorota Gertig Anna DeFazio David D L Bowtell

PURPOSE The study aim to identify novel molecular subtypes of ovarian cancer by gene expression profiling with linkage to clinical and pathologic features. EXPERIMENTAL DESIGN Microarray gene expression profiling was done on 285 serous and endometrioid tumors of the ovary, peritoneum, and fallopian tube. K-means clustering was applied to identify robust molecular subtypes. Statistical analysi...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2011
Kieron Dunleavy Wyndham H Wilson

Gene expression profiling has been used to divide diffuse large B-cell lymphoma into distinct molecular subtypes with different outcomes following immunochemotherapy. Recently, researchers have shown much interest in investigating the role of biomarkers, such as BCL2, in predicting outcome in diffuse large B-cell lymphoma, particularly in the context of these molecular subtypes.

Journal: :Surgical Oncology Clinics of North America 2018

Journal: :Trends in microbiology 1998
A M Vandamme M Salemi J Desmyter

At least four, and possibly six, molecular subtypes of human T-cell lymphotropic virus type I (HTLV-I) exist: one is confined to Melanesia/Australia, one is ubiquitous, and the others are found only in Africa. Molecular epidemiology suggests that all subtypes arose from separate interspecies transmissions from simians to humans.

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