OBJECTIVE To help develop an evidence-based approach to the best management of twin pregnancies discordant for anencephaly. METHODS We retrospectively examined the management and outcome of 18 pregnancies discordant for anencephaly diagnosed at 11 + 0 to 13 + 6 weeks of gestation in our center. We combined these data with those from other publications. In total, there were 44 dichorionic preg...

OBJECTIVE To evaluate the perinatal outcome of MC twins with selective IUGR (sIUGR). STUDY DESIGN A prospective study, which included three groups of MC twins: Group A, uncomplicated MC twin pregnancies (n = 91); group B, sIUGR with normal umbilical artery Doppler (n = 19); and group C, sIUGR with abnormal (absence or reversed EDV) umbilical artery Doppler (n = 18). The latter were routinely ...

This study examines the value of assessing inter-twin membrane folding in monochorionic twin pregnancies in the prediction of twin-to-twin transfusion syndrome. In 83 monochorionic twin pregnancies ultrasound scans were carried out at 10-14, 15-17 and 19-21 weeks to investigate folding of the inter-twin membrane as an early sonographic feature of inter-twin discrepancy in amniotic fluid volume....

OBJECTIVE To determine whether in screening for trisomy 21 by measurement of fetal nuchal translucency (NT) thickness in monochorionic twin pregnancies it is preferable to use the higher, smaller or average NT. METHODS We retrospectively examined 769 monochorionic twin pregnancies that had undergone NT screening. The selection criteria were that first, in each pregnancy both fetuses were aliv...

BACKGROUND Monochorionic twin pregnancies are at increased risk of complications due to sharing a single placenta and potentially developing unbalanced vascular anastomoses. Complications include twin-twin transfusion syndrome (TTTS) which affects 10-15% monochorionic twins, and if untreated has a 70-90% perinatal loss rate. We are currently unable to predict which twins will develop complicati...

PATIENT Female, 28 FINAL DIAGNOSIS: Single intrauterine fetal death Symptoms: - MEDICATION - Clinical Procedure: - Specialty: Obstetrics and Gynecology. OBJECTIVE Rare disease. BACKGROUND Single fetal death in monochorionic twin pregnancy may result in poor perinatal outcome of the surviving twin, including neurologic sequelae, other organ injury, and death. In most reported cases of poor...

Monochorionic fetuses are traditionally thought of as monozygotic (MZ), arising from a single embryo that splits during early embryogenesis. With rare exception, they typically exhibit the same genotype and the same gender. However, several recent reports have documented that monochorionicity does not always indicate monozygosity (Souter et al., 2003). At least 14 such cases have been reported ...