Given the current explosion of knowledge of the genetics and molecular biology of cancer, the possibility of widespread testing for inherited predisposition to cancer has been raised. The main objective of this study was to assess the effect of inherited predisposition on cancer mortality among the National Academy of Sciences-National Research Council Twin Registry. The twins were white male U...

Dr Sommer and colleagues (2004) reported decreased language lateralisation measured with functional magnetic resonance imaging (fMRI) in 12 monozygotic twin pairs discordant for schizophrenia compared with 12 healthy monozygotic twin pairs. The authors did not find significant differences in language lateralisation between affected twins and their co-twins without schizophrenia. In the December...

ône-third of population deal with sleep disorders which might be due to social, economic or medical problems. studies on twins have indicated the role of genetic factors in these disorders. monozygotic twins have a very similar hypnogram. â higher prevalence of some sleep disorders is reported in relatives of the patients with these disorders. genes also affect sleep disorders as well as some o...

Fellman and Eriksson (2010) cited my suggestion that the sex ratio (proportion male) of monozygotic (MZ) twins is lower than that of dizygotic (DZ) twins (James 1975). Here I offer elaborations on and potential explanations for this.

INTRODUCTION Conjoined twins are identical twins joined in utero. It's a rare phenomenon and present a unique challenge to obstetricians and pediatric surgeons. Conjoined twins are complex complication of monozygotic twinning, which is associated with high perinatal mortality. CASE REPORT At our clinic complete anomaly scan was done, the patients was found to have monozygotic twins of 15 week...

The ages of onset in multiple sclerosis cases span more than 7 decades. Data are presented for affected relative pairs from a Canadian population base of 30,000 multiple sclerosis index cases (1993-2008). The effects of genetic sharing, parent of origin, intergenerational versus collinear differences, and gender on the ages of onset were evaluated in the following concordant pairs: monozygotic ...

The influence of genes and environment on the association between bipolar disorder (BD) and volumes of subcortical brain regions involved in emotion processing has rarely been studied. Furthermore, as far as we know, longitudinal twin studies of subcortical brain volume change in BD have not been carried out at all. In this study, we focused on the genetic and environmental contributions to cro...

BACKGROUND The human endogenous retroviral family W, Env(C7), member 1 gene (HERVWE1) is thought to participate in trophoblast cell fusion, and its expression is diminished in the placentas of singleton intrauterine growth-retarded pregnancies. However, there is limited information about the role of HERVWE1 in discordant fetal growth in twins. This study was to compare HERVWE1 gene expression b...

Background Use or abuse of opioids and related drugs during pregnancy increases the risk of maternal and neonatal morbidities, including increased susceptibility to Neonatal Abstinence Syndrome (NAS). Severity of NAS is determined by both environmental and genetic factors, but the level of influence each one of them has in determining the severity of NAS is not fully understood. Since the incid...

This report details the case of 17 year old identical twins who both presented with paroxysmal supraventricular tachycardia (PSVT). Electrophysiological studies revealed atrioventricular nodal reentry tachycardia (AVNRT) in both twins. Successful but technically challenging slow pathway ablation was performed in both twins. This is the first reported case of confirmed AVNRT in identical twins w...