Chronic myeloid leukemia (CML) is characterized by BCR-ABL translocation and an increased number and migration of immature myeloid cells into the peripheral blood. The detection limit of the BCR-ABL transcript, particularly after treatment, is controversial. In the present study, we used quantitative real-time reverse transcription-polymerase chain reaction (RT-qPCR) to monitor BCR-ABL expressi...

Soil fungi associated with plant roots, notably ectomycorrhizal (EcM) fungi, are central in above- and below-ground interactions in Mediterranean forests. They are a key component in soil nutrient cycling and plant productivity. Yet, major disturbances of Mediterranean forests, particularly in the Southern Mediterranean basin, are observed due to the greater human pressures and climate changes....

In the last five years, Moroccan e-health system has focused on improving the quality of patient care services by making use of advanced Information and Communications Technologies (ICT) solutions. In actual fact, achieving runtime and efficient information sharing, through large-scale distributed environments such as e-health system, is not a trivial task. It seems to present many issues due t...

BACKGROUND Although not as common as in women, osteoporosis remains a significant health care problem in men. Data concerning risk factors of osteoporosis are lacking for the male Moroccan population. The objective of the study was to identify some determinants associated to low bone mineral density in Moroccan men. METHODS a sample of 592 healthy men aged 20-79 years was recruited from the a...

The Moroccan state has long attempted to maintain tight control on “its” subjects living in Europe. Since the 1960s, the state has actively discouraged migrants’ social and political integration because this was seen as endangering the flow of remittances and creating political opposition from outside. However, the failure of these remote control policies and an ominous stagnation in remittance...

BACKGROUND Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor intimately associated with Epstein-Barr virus (EBV). NPC is a characteristic tumor displaying epidemiological, genetic and regional distribution properties that makes it unique by its natural behavior. OBJECTIVES To assess the expression pattern of LMP1 and p53 proteins in the different histological types of NPC in a sa...

BACKGROUND Since 1998 Municipal Public Health Services (MPHSs) in The Netherlands carried out Hepatitis A (HAV) vaccination programs for Turkish and Moroccan children to reduce import and secondary HAV infections. The aim of this study was to assess the effects of the programs on HAV incidence. METHODS MPHSs were questioned about HAV vaccination programs for migrant children. Notification dat...

AIMS AND OBJECTIVES To gain insight into the factors that influence communication between health professionals and Turkish and Moroccan immigrants in the palliative phase of cancer. BACKGROUND In palliative care, communication is crucial. The question, however, is whether Dutch healthcare providers, on the one hand, and Turkish and Moroccan patients and their family members, on the other, agr...

Background. In lung adenocarcinoma, the frequency of KRAS mutations is ethnicity dependent with a higher proportion in African Americans and white Caucasians than in Asians. The prevalence of these mutations among North Africans patients is unknown. The objective of this study was to report the frequency and spectrum of KRAS mutations in a group of Moroccan lung adenocarcinoma patients. Methods...

Background. The LRRK2 G2019S mutation is the most common genetic determinant of Parkinson's disease (PD) identified to date. This mutation, reported in both familial and sporadic PD, occurs at elevated frequencies in Maghreb population. In the present study, we examined the prevalence of the G2019S mutation in the Moroccan population and we compared the motor and nonmotor phenotype of G2019S ca...