We report on a diastereoselective synthesis of six derivatives of caffeoyl- and feruloyl-muco-quinic acids. All the muco-quinic acid derivatives were obtained in excellent yield in five steps starting from quinic acid, caffeic acid and ferulic acid. Allyl ether protection of trans-hydroxy cinnamic acids was here introduced to chlorogenic acids synthesis. We show that muco-quinic acid derivative...

Background and aim: Adult T cell leukemia/lymphoma (ATLL) is an aggresive malignancy which may occur in human T lymphotropic virus1(HTLV1) infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant number of patients, we studied ATLL patients in Mashhad.Mate...

Cutaneous metastases of prostate cancer are a rare entity and mimic many other common cutaneous conditions such as cellulitis, zosteriform lesions, others, making it easy to misdiagnose. Recognition this condition is vital prevent delays in treatment, lesions usually appear late stages the disease associated with high fatality rate. Here we describe case 64-year-old man history diffuse metastat...

BACKGROUND The global prevalence of premalignant lesions has been continuously increasing in recent years, but there has been little research regarding the distribution and incidence of cutaneous premalignant lesions in Korean populations. OBJECTIVE We conducted this retrospective study to analyze recent trends in the incidence and clinical patterns of cutaneous premalignant lesions in the Ko...

Primary cutaneous actinomycosis is very uncommon. We report a patient with cutaneous actinomycosis with multiple lesions without any detectable extra-cutaneous lesions. In our patient the actinomycosis was the presenting manifestation of HIV infection.

phaeohyphomycosis is an amalgam of clinical diseases caused by a wide variety of dematiaceous fungi. we are reporting on a 16 year-old patient from amol with subcutaneous cervical nodes and nasopharyngeal lesions of phaeohypho mycosis that were confirmed by pathological examination, direct smear, and culture. after treatment with an oral triazole (itraconazole) for 4 months, all nodes and lesio...

A 71-year-old woman, receiving treatment for type 2 diabetes mellitus, hypertension, and hypercholesterolemia, had suffered an ethanol burn affecting the facial, anterior cervical, and neckline region 7 years earlier. She consulted the outpatient department for inflammation and pruritus in the scars that began 4 months earlier. She also presented new lesions on healthy skin, but no associated s...

Vascular anomalies are lesions seen in all surgical disciplines, particularly in pediatric patients. Specialization in vascular anomalies involves a team effort, with the team consisting of plastic surgeons, general surgeons, neurosurgeons, pediatricians, interventional radiologists, dermatologists, ophthalmologists, otolaryngologists, hematologists, and pathologists. Inconsistent nomenclature ...