In this paper, we solve a combinatorial optimization problem that arises from the treatment planning of a type of radiotherapy where intensity is modulated by multileaf collimators in a step-and-shoot manner. In Ernst et al. [INFORMS Journal on Computing 21:4 (2009) 562–574], we proposed an exact method for minimizing the number of multileaf collimator apertures needed for a treatment. Our meth...

Objective: Modelling linear accelerator (linac) photon beams using the Monte Carlo (MC) technique is presently most precise with which to calculate radiotherapy beam data. Complicated treatment plans can be achieved by Agility multileaf collimator. The focus of this study model a linac, integrated an head, EGSnrc MC code and investigate its accuracy compared actual measurements. Methodology: A ...