rho-kinase is an effector molecule of rhoa, a monomeric gtp-binding protein, and causes ca2+ sensitization through inactivation of myosin phosphatase. the major physiological functions of rho/rho-kinase cascade include contraction, proliferation and migration in cells.there are some excellent reviews about rho/rho-kinase signal pathway, most of which focus on the specific proteins of the pathwa...

background: bisphenol a (bpa) is one of the hazardous materials causing disruption of endocrine pathways. due to water contamination by this component from multiple sources and the associated health problems, bpa has been the focus of multiple studies. it has been proved that bpa may cause harm because of its impact on estrogenic receptors in human and other organisms. methods: in this study, t...