in this paper, the bernstein polynomials are used to approximate the solutions of linear integral equations with multiple time lags (iemtl) through expansion methods (collocation method, partition method, galerkin method). the method is discussed in detail and illustrated by solving some numerical examples. comparison between the exact and approximated results obtained from these methods is...

background: statins, widely used cholesterol-lowering agents, have also been demonstrated to have anti-inflammatory and immunomdulatory effects. objective: to evaluate the effects of atorvastatin in combination with interferon-β in the treatment of multiple sclerosis (ms) in a randomized controlled clinical trial. methods: multiple sclerosis patients were randomized independently, in a double b...

background: there is a known inverse association between solar radiation and the prevalence of multiple sclerosis (ms). some studies have investigated the link between vitamin d and ms. the aim of this study was to investigate the possible association between serum 25(oh) vitamin d3 concentration and the severity of disease in iranian patients with ms. methods: patients with relapsing-remitting...

Objectives—The commonly employed outcome measures on disability and relapse rates in treatment trials of relapsing-remitting multiple sclerosis have well demonstrated sensitivity to treatment eVects, but their clinical interpretation is problematic. An alternative method of analysis, which is more clinically meaningful and statistically appropriate to a condition with a fluctuating disease cour...