using complement fixation technique, serial serum samples from 15 patients undergoing surgical removal of malignant tumors were assayed for the presence of tumors antibodies against the cellular fractions of both normal and carcinomatous tissue. antibody responses against tumor associated antigens were detected in four cases. in all cases antibody activity was directed only against the supernat...

BACKGROUND Diffusion-weighted imaging (DWI) is a noninvasive method for investigation of tumor histological content. It has been applied for some musculoskeletal tumors and reported to be useful. OBJECTIVES The aim of the present study was to prospectively evaluate the apparent diffusion coefficient (ADC) values of benign and malignant soft tissue tumors and to determine if ADC can help diffe...

background and aims. head and neck tumors are the most common complaints of people referring to different medical sections, especially in children. the aim of this study was to evaluate the prevalence of these tumors in children less than 12 years of age to provide a better perspective for future studies. materials and methods. all the files in department of pathology at tabriz pediatric hospit...

background: understanding the differences in genetics of malignancies is crucial for therapeutic decisions. this systematic review was conducted to evaluate the current evidence on genetics of bone tumors in the context of pediatric cancer. material and methods: we performed a systematic review of the literature published on genetics of pediatrics bone tumors, using pubmed, google scholar, scie...

metallothionein (mt) manifests varying expression levels in carcinomas, and they may be considered as valuable cell cancerization biomarkers for diagnosis of patients with cancers. a meta-analysis was conducted to evaluate comprehensively the mt expression difference in various benign tumors and malignant tumors, which compared the high with low mt expression levels in patients of the available...

The manuscripts in this thematic issue on musculoskeletal oncology present different techniques and address difficult topics that have received limited attention in the current literature. Because of the wide variety of clinical situations encountered with bone and soft tissue tumors, it is essential for oncologic surgeons to be both facile and versatile. The following manuscripts contain valua...

Individuals involved in sports are at risk for sustaining various injuries. In addition to musculoskeletal complaints, male athletes are at risk of incurring testicular injuries. These issues can range from an acute emergency such as testicular torsion to indolent testicular tumors. In contrast, epididymitis can present in stages. Presentation and management of testicular complaints can vary de...

Although the value of MRI in the evaluation of musculoskeletal conditions such as tumors, osteonecrosis, and inflammatory processes was apparent almost immediately after the introduction of this modality in the early 1980’s, early studies of knee imaging with MRI were inconclusive. Knee imaging was a more technically-demanding application of MRI, and the capabilities of the early low field syst...

Tumors of the foot and ankle are rare, and the particular clinicopathologic features, therapeutic approach, and outcomes in this setting are not well established. From January 2000 to December 2010, 72 patients with primary musculoskeletal tumors of the foot and ankle, both benign and malignant, were treated at a single institution. Of the 72 patients, 56% were female. The median age was 52 yea...