نتایج جستجو برای: myocyte enhancer factor 2

تعداد نتایج: 3167311  

Journal: :Canadian Journal of Cardiology 2023

Genome-wide association studies have identified single-nucleotide polymorphisms (SNPs) in the Unc51-like-kinase 4 (ULK4) gene, to be associated with blood pressure. Aims (i) replicate and validate previously reported associations between ULK4 gene hypertension on hypertensive cases normotensive controls, (ii) identify silico potential functionality of variants. A total 558 genotyped Caucasian s...

Journal: :Circulation research 2009
Yasuaki Nakagawa Koichiro Kuwahara Genzo Takemura Masaharu Akao Masashi Kato Yuji Arai Makoto Takano Masaki Harada Masao Murakami Michio Nakanishi Satoru Usami Shinji Yasuno Hideyuki Kinoshita Masataka Fujiwara Kenji Ueshima Kazuwa Nakao

RATIONALE It is known that the transcriptional coactivator p300 is crucially involved in the differentiation and growth of cardiac myocytes during development. However, the physiological function of p300 in the postnatal hearts remains to be characterized. OBJECTIVE We have now investigated the physiological function of p300 in adult hearts. METHODS AND RESULTS We analyzed transgenic mice e...

رجبی, حمید, سلیمانی, مسعود, فتحی, محمد, قراخانلو, رضا,

Introduction: Myocyte Enhancer Factor 2 (mef2) gene relates with multiple myogenic transcriptional factors that induces activation Muscle-specific genes. MEF2 contributes in muscular cells development and differentiation as well as in fibers transition in response to stimulants. Therefore, the aim of this study was to evaluate the effect of one bout of resistance exercise (RE) on mef2 gene expr...

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