Abstract. The Paleocene–Eocene Thermal Maximum (PETM; ∼ 55.9 Ma) was a period of rapid and sustained global warming associated with significant carbon emissions. It coincided the North Atlantic opening emplacement Igneous Province (NAIP), suggesting possible causal relationship. Only very limited number PETM studies exist from Sea, despite its ideal position for tracking impact both changing cl...

Fifty outbred Syrian golden hamsters were equally divided into three experimental groups and two control groups. The pouches of the experimental groups were painted bilaterally with a 0.5% 7,12-dimethylbenz[a]anthracene (DMBA) solution thrice a week for 3, 7 and 14 weeks. One of the control groups was applied with mineral oil while another control group remained untreated throughout the experim...

Myeloid cells assemble inflammasomes in response to infection or cell damage; cytosolic sensors activate pro-caspase-1, indirectly for the most part, via the adaptors ASC and NLRC4. This leads to secretion of proinflammatory cytokines and pyroptosis. To explore complex formation under physiological conditions, we generated an alpaca single domain antibody, VHHASC, which specifically recognizes ...