Nur77 is a member of the steroid receptor superfamily and is known to be expressed in animals under stress. We studied the role of nur77 in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis during the stress response using a murine pituitary corticotrope cell line, AtT-20. Corticotropin-releasing hormone (CRH), a stress mediator in the HPA axis, induced the expression of nur77 tra...

Conduction of ions through the NaK channel, with M0 helix removed, was studied using both Brownian dynamics and molecular dynamics. Brownian dynamics simulations predict that the truncated NaK has approximately a third of the conductance of the related KcsA K+ channel, is outwardly rectifying, and has a Michaelis-Menten current-concentration relationship. Current magnitude increases when the gl...

Nobuyuki Wada ([email protected]) Kiminori Sugino ([email protected]) Takashi Mimura ([email protected]) Mitsuji Nagahama ([email protected]) Wataru Kitagawa ([email protected]) Hiroshi Shibuya ([email protected]) Keiko Ohkuwa ([email protected]) Hirotaka Nakayama ([email protected]) Shohei Hirakawa ([email protected]) Yasushi Rino (rino...

Given a prime p and distinct non-zero integers a1, a2, . . . , ak (mod p), we investigate the number N = N(a1, a2, . . . , ak; p) of residues n (mod p) for which (na1)p < (na2)p < . . . < (nak)p, where (b)p is the least non-negative residue of b (mod p). We give complete solutions to the problem when k = 2, 3, 4, and establish some general results corresponding to k ≥ 5. 2000 Mathematics Subjec...

Collisional satellite lines with |ΔJ| ≤ 58 have been identified in recent polarization spectroscopy V-type optical-optical double resonance (OODR) excitation spectra of the Rb(2) molecule [H. Salami et al., Phys. Rev. A 80, 022515 (2009)]. Observation of these satellite lines clearly requires a transfer of population from the rotational level directly excited by the pump laser to a neighboring ...

Liquid metals Li, Na and NaK are the candidate heat transfer mediums which installed in irradiation capsule of advanced fusion neutron source. The compatibility issue F82H 316L was studied by means corrosion tests at temperature up to 823 K. depletion Cr, C Fe from steel caused liquid Li. Li diffusion into matrix analyzed TOF-SIMS. surface oxidation. similar with that Na.

We propose a basic mobile multicast scheme in Mobile IPv6 called previous network subscription (PS). In PS, when a mobile host moves to a new foreign network, it will build a bi-directional tunnel with its previous network, so mobile host can continue to receive multicast packets soon after handover. We also propose a new reliable mobile multicast protocol called RRHMoM (Reliable Region based H...

A novel plant protein kinase, designated Brassica napus kinase 1 (BNK1), was isolated from a lambda-pistil cDNA library. The deduced BNK1 protein contains all eleven conserved subdomains of a kinase and encodes a functional serine/threonine protein kinase. Phylogenetic analysis of several plant protein kinase subfamilies showed that BNK1 is most closely related to the NAK subfamily of protein k...

HeLa cell plasma membranes have been purified after binding cells to polylysine-coated polyacrylamide beads. Cell attachment to beads and membrane recovery were maximal in a sucrose-acetate buffer, pH 5.0, at 25 degrees C. Measurements of ouabain-sensitive NaK-adenosine triphosphatase, membrane-bound 125I-wheat germ agglutinin, and chemical analyses showed that membranes on beads were of compar...