Abstract Researches proving methods for nano-encapsulation of neonatal porcine islet-like cell clusters (NPCCs) using polymersomes (PSomes) formed polymers polyethylene glycol-block-poly lactide. Herein, our studies present efficient procedure with minimal damage and loss NPCCs.We used N-hydroxysuccinimide (NHS) on the N-terminal PSomes to induce binding amine groups in extracellular matrix sur...

Many chemotherapeutic regimens have been investigated for advanced unresectable and metastatic pancreatic cancer (PC), but with only minimal improvement in survival prognosis. Here, we anti-cancer function of free nano-encapsulated hydroxytyrosol (Hyd) curcumin (Cur), its combinations (Hyd-Cur) on PANC-1 cell line. The poly lactide-co-glycolide-co-polyacrylic acid (PLGA-co-PAA) Hyd Cur were syn...

Polymer nanoparticles are vehicles used for delivery of hydrophobic anti-cancer drugs, like doxorubicin, paclitaxel or chemopreventors like quercetin (Q). The present study deals with the synthesis and characterisation of nano formulations (NFs) from Q loaded PLGA (poly lactic-co-glycolic acid) nano particles (NPs) by surface modification. The surface of Q-loaded (NPs) is modified by coating wi...

Reverse micelles present self-assembled multi-molecular entities formed within specific compositional ranges of water-in-oil microemulsions. The structure of a reverse micelle is typically represented as nano-sized droplet of a polar liquid phase, capped by a monolayer of surfactant molecules, and uniformly distributed within a non-polar, oil phase. Although their role in serving as primitive m...

Nanostructures Formulation for Food Products: Advances in soft matter nanotechnology are increasingly being realised to offer smart and generic solutions in various production fields including food and agriculture industries [1]. In recent years there have been several studies reporting on nano medicinal applications of Lyotropic liquid crystalline (LLC) phases like in development of novel cont...

Nanomedicine is becoming very popular over conventional methods due to the ability to tune physico-chemical properties of nano vectors, which are used for encapsulation of therapeutic and diagnostic agents. However, the success of nanomedicine primarily relies on how specifically and efficiently nanocarriers can target pathological sites to minimize undesirable side effects and enhance therapeu...

the aim of the research work was to chemically modify guar gum(gg) as a ph sensitive co-polymer and formulating intestinal targeting eso nanoparticles (nps) using the synthesized co-polymer. poly acrylamide-grafted-guar gum (paam-g-gg) co-polymer was synthesized by free radical polymerization. chemical modification of paam-g-gg by alkaline hydrolysis results in formation of a ph-sensitive co-po...

Natural Anticancer Agents Cancer is the second leading cause of death throughout world. In article number 2209419, Hadis Rostamabadi and co-workers, comprehensively overview biopolymer nanovehicles for oral delivery natural anticancer agents (NAAs). NAAs that are a gift nature to humanity, have been extensively utilized in alleviation/prevention cancer. The restricted by some inherent features ...