Isothermal nucleic acid amplification strategies have been combined with nanotechnology for advanced biosensing, material design, and biomedical applications. However, merging phenomena materials of different nanoscales the aim exploiting all their benefits at once has remained a challenging endeavor. Here, we exemplify various problems one can encounter when combining nanodimensions lanthanide...

in this study, we explained a nanobiosensor for dna sequence detection, featuring sequence specificity, cost efficiency, speed, and ease of use. without the need for labels or indicators, it may be ideal for the detection of biological agents. this review describes recent advances in electrochemical impedance spectroscopy (eis) with an emphasis on using nanoparticles and nanotechnology. a power...

In this article, we propose a Flexure-FET (flexure sensitive field effect transistor) ultrasensitive biosensor that utilizes the nonlinear electromechanical coupling to overcome the fundamental sensitivity limits of classical electrical or mechanical nanoscale biosensors. The stiffness of the suspended gate of Flexure-FET changes with the capture of the target biomolecules, and the correspondin...

Modern label-free biosensors are generally far more sensitive and require orders of magnitude less incubation time compared to their classical counterparts. However, a more important characteristic regarding the viability of this technology for applications in genomicsproteomics is defined by the "Selectivity," i.e., the ability to concurrently and uniquely detect multiple target biomolecules i...

The use of agrochemicals has increased considerably in recent years, and consequently, there has been increased exposure of ecosystems and human populations to these highly toxic compounds. The study and development of methodologies to detect these substances with greater sensitivity has become extremely relevant. This article describes, for the first time, the use of atomic force spectroscopy ...

The discovery of new bioactive compounds to treat microbial infections is an ever increasing need as a result of the constant evolution of resistance by the infectious agents, notably malaria and pathogenic bacteria. By using a nanotechnology approach based on Chemical Force Microscopy, a derivation of Atomic Force Microscopy that allows the measurement of interaction forces between single mole...

Here, fundamental aspects affecting template-assisted engineering of oxidase-associated peroxide oxidation co-catalysis the modeled microanalytical system based on hybrid palladium nanoparticles (Pd-NPs) with tailored functional properties were studied. By an accurate tuning and validation experimental setup, a modular Pd-NPs-doped one-pot/one-electrode amperometric nanobiosensor for advanced m...