Perthiolated β-cyclodextrin-based nanocapsules incorporating diaquo Gd(III)-complexes represent a promising new type of bioresponsive MRI contrast agent, showing a pronounced relaxivity change upon degradation in a reducing environment.

Stable carbohydrate-coated nanocapsules designed as multivalent nanoscaffolds for selective interactions with receptors are able to encapsulate guest molecules within their interior and to bind efficiently to FimH adhesin of bacterial type 1 pili.

Nanorattles made of hollow polymer nanocapsules with entrapped silver nanoparticles were synthesized in one step by using lipid vesicles as templates. Free radical photoinitiator facilitated both polymerization within the bilayer and formation of metal nanoparticles in the aqueous core.

A stable aqueous dispersion of hybrid silica nanocapsules encapsulating fluorescent conjugated polymers have been successfully synthesized via a facile and highly benign approach of templated condensation of silica precursors at the core-corona interface of PEO-based block copolymer micelles.

Core/shell nanomaterials composed of only polypyrroles (PPys) were fabricated by microemulsion polymerization using two oxidants with different chemical oxidation potentials, and used as a precursor for the fabrication of PPy and carbon nanocapsules.

BACKGROUND Drug nano-carriers are one of the most important tools for targeted cancer therapy so that undesired side effects of chemotherapy drugs are minimized. In this area, the use of ultrasound can be helpful in controlling drug release from nanoparticles to achieve higher treatment efficiency. OBJECTIVE Here, we studies the effects of ultrasound irradiation on the release profile of 5-fl...

Considering that Alzheimer's disease is a prevalent neurodegenerative disease worldwide, we investigated the activities of three key kinases: creatine kinase, pyruvate kinase and adenylate kinase in the hippocampus and cerebral cortex in Alzheimer's disease model. Male adult Swiss mice received amyloid-β or saline. One day after, mice were treated with blank nanocapsules (17 ml/kg) or meloxicam...

To detect biochemicals with ultrahigh sensitivity, efficiency, reproducibility, and specificity has been the holy grail in the development of nanosensors. In this work, we report an innovative type of photonic-plasmonic hybrid Raman nanosensor integrated with electrokinetic manipulation by rational design, which offers dual mechanisms that enhance the sensitivity for molecule detection directly...

Post-thawing cryoinjuries in boar spermatozoa due to oxidative stress may be reduced by adding nanoencapsulated antioxidants freezing extenders. This study evaluated post-thawing kinetics, structural and biochemical functions of frozen with extenders including resveratrol vitamin E loaded into polymeric nanocapsules. Resveratrol was added at 0 (control), 5, 10, 20, 40 80 µg/ml, whereas Vitamin ...