During the summer of 2022, symptoms witches’-broom, flowering malformation and redness were observed in lettuce plants (Lactuca sativa) fields Cordoba Province, Argentina (Fig. 1a). In same fields, garlic (Allium sativum) exhibiting phyllody 1b-c) also observed. To confirm presence phytoplasma, leaf samples from two diseased three collected. As negative controls, symptomless (one garlic) Total ...

Abstract Study question How are the semen microbiota compositions of patients with asthenozoospermic and normozoospermic different, According to data from 16S rRNA gene-specific Next-generation sequencing (NGS)? Summary answer Large numbers microbes can be present in seminal fluid, there differences between samples. What is known already Male factor attributable up 50% cases infertility. Most s...

Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by over-activity of lymphocytes, production autoantibodies and effects on multiple organs 1. Growing evidences suggest long noncoding RNAs (lncRNAs) mRNAs widely participate in physiological pathological processes. However, knowledge related lncRNAs SLE remains limited. Objectives The aim our study to in...

New drugs are continuously being developed for the treatment of patients with estrogen receptor-positive breast cancer. Thymoquinone is one of the drugs that exhibits anticancer characteristics based on in vivo and in vitro models. This study further investigates the effects of thymoquinone on human gene expression using cDNA microarray technology. The quantification of RNA samples was carried ...

Geminiviruses are a group of plant viruses that contain circular single stranded (ss) DNA genomes encapsidated in small twinned icosahedral capsids .The virus DNA A plus strand encodes the coat protein (CP/AV1) essential for viral transmission by whiteflies (Bemisia tabaci)[4]. Jatropha has been found to have strong molluscicidal activity and the latex to be strongly inhibitory to watermelon mo...

Treatment of Staphylococcus aureus infections has become increasingly challenging due to the rise of antibiotic-resistant strains. Therefore, development of antibiotic-independent treatments that supplement or provide an alternative approach to traditional therapies is greatly needed. One promising approach is the development of ‘antipathogenic’ therapies that inhibit bacterial virulence. Quoru...

hepatitis c virus is one of the main reasons for chronic liver disease and hepatocellular carcinoma. combination therapy with interferon (peg-ifn-α) and ribavirin (rbv) clear the virus more likely than the others. different factors like virus and host characteristics influence on response to treatment. the most important viral factors include virus genotype and viral load; host factors like gen...

Background The pathophysiology of Takayasu arteritis (TAK) is incompletely understood. Gene expression profile peripheral blood mononuclear cells (PBMCs) in TAK has been scarcely studied and may provide new insights into its pathogenesis. Objectives To identify functionally annotate differentially expressed genes (DEGs) immunosuppressive-naïve compared with healthy controls (HCs). Methods Fifte...

introduction butyrivibrio fibrisolvens strains are presently recognized as the major butyrate-producing bacteria found in the rumen and digestive track of many animals and also in the human gut. in this study we reported the development of two dna based techniques, quantitative competitive (qc) pcr and absolute based real-time pcr, for enumerating butyrivibrio fibrisolvens strains. despite the ...

Objectives: Circulating microRNAs (miRNAs) are promising as biomarkers for various diseases. We examined the release patterns of cardiospecific miRNAs in a closed-chest, large animal ischemia-reperfusion model and in patients with ST elevation myocardial infarction (STEMI). Methods: Six anesthetized pigs were subjected to coronary occlusion-reperfusion. Plasma, urine, and clinical parameters we...