Fondaparinux (Fpx) is the anticoagulant of choice in the treatment of short- and medium-term thromboembolic disease. To overcome the low oral bioavailability of Fpx, a new nanoparticulate carrier has been developed. The nanoparticles (NPs) contain squalenyl derivatives, known for their excellent oral bioavailability. They spontaneously self-assemble upon both electrostatic and hydrophobic inter...

biosynthesis of silver nanoparticles with small size and biostability is very important and used in various biomedical applications. in the present work, we describe the synthesis of silver nanoparticles (ag-nps) using seed aqueous extract of olea europaea (oe) and its antibacterial activity. uv–visible spectroscopy, x-ray diffraction (xrd), transmission electron microscopy (tem), scanning elec...

we report the direct soft chemical synthesis and characterization of a family of face centered cubic (fcc) and partially ordered face centered tetragonal (fct) fept nanoparticles (nps) suitable for biomedical applications. both fcc and partially ordered fct-fept nps are synthesized by employing a simple polyol method. by using polyvinyl pyrolidone (pvp) as a stabilizer in various ratios during ...

The bioprocessing of CeO2 nanoparticles after uptake in lung tissues is compared with the formation of nanoparticles after inhalation of CeCl3 aerosols. In both cases, high-resolution TEM/STEM analyses indicate that cerium phosphate nanoparticles (NPs) had precipitated in phagolysosomal regions within macrophages. Importantly, the primary particle size, morphology, and agglomeration tendencies ...

In this article, it is shown that the efficiency of an electrochemical aptasensing device is influenced by the use of different nanoparticles (NPs) such as gold nanoparticles (Au), silver nanoparticles (Ag), hollow gold nanospheres (HGN), hollow silver nanospheres (HSN), silver–gold core shell (Ag@Au), gold–silver core shell (Au@Ag), and silver–gold alloy nanoparticles (Ag/Au). Among these nano...

The development of different kinds of nanoparticles, showing different physico-chemical properties, has fostered their large use in many fields, including medicine. As a consequence, inorganic nanoparticles (e.g., metals or semiconductors), have raised issues about their potential toxicity. The scientific community is investigating the toxicity mechanisms of these materials, in vitro and in viv...

The diverse mechanism of antimicrobial activity of Ag and AgBr nanoparticles against gram-positive and gram-negative bacteria and also against several strains of candida was explored in this study. The AgBr nanoparticles (NPs) were prepared by simple precipitation of silver nitrate by potassium bromide in the presence of stabilizing polymers. The used polymers (PEG, PVP, PVA, and HEC) influence...

Silver nanoparticles display unique physical and biological properties which have attracted intensive research interest because of their important medical applications. In this study silver nanoparticles (Ab.Ag-NPs) were synthesized for biomedical applications using a completely green biosynthetic method using Achillea biebersteinii flowers extract. The structure and properties of Ab.Ag-NPs wer...

objective(s):   metal nanoparticles (nps) offer a wide variety of potential applications in pharmaceutical sciences due to the unique advances in nanotechnology research. in this work, bimetal ag-au alloy nps were prepared and their combinations with other antibiotics were tested against staphylococcus aureus.   materials and methods: firstly, ag-au alloy nps with au/ag molar ratio of 1:1 was f...

UNLABELLED BACKGROUND This study aims to investigate the influence of different stirring times on antibacterial activity of silver nanoparticles in polyethylene glycol (PEG) suspension. The silver nanoparticles (Ag-NPs) were prepared by green synthesis method using green agents, polyethylene glycol (PEG) under moderate temperature at different stirring times. Silver nitrate (AgNO3) was taken...