INTRODUCTION Testicular torsion and detorsion causes reperfusion injury which damages the testicular tissue and affects the quality of sperm. Deterioration in the quality of sperm worldwide is the recent scenario and one of its reasons is testicular ischemic/ reperfusion (IR) injury. Therefore the present study aims at producing new drugs for the treatment of testicular IR injury. METHODS 42 ...

Mục tiêu: Xây dựng quy trình định lượng đồng thời naringin và hesperidin trong quả bưởi non bằng LC-MS/MS. Đối tượng phương pháp: Naringin non. Quy được xây thẩm pháp sắc ký lỏng đầu dò MS/MS. Kết quả: Điều kiện ký: cột C8, pha động methanol – acid acetic 0,1% (50 : 50), tốc độ dòng 0,6 ml/phút, nhiệt 30oC, buồng tiêm mẫu 10oC, thể tích 5 μl phát hiện MS/MS ở chế ESI (-), MRM. đạt các chỉ tiêu ...

The effects of six flavonoids viz., apigenin, genistein, morin, naringin, pelargonidin and quercetin on the susceptibility of low-density lipoprotein (LDL) to oxidative modification were investigated. Flavonoids were added to plasma and incubated for 3 hr at 37 degrees C, and the LDL fraction was separated by ultracentrifugation. Oxidizability of LDL was estimated by measuring conjugated diene ...

objective: metals can cause male infertility through affection of spermatogenesis and sperm quality. strong evidences confirm that male infertility in metal-exposed humans is mediated via various mechanisms such as production of reactive oxygen species (ros). flavonoids have antioxidant and metal chelating properties which make them suitable candidates for neutralizing adverse effects of metals...

background: testicular torsion and detorsion causes reperfusion injury which damages the testicular tissue and affects the quality of sperm. deterioration in the quality of sperm worldwide is the recent scenario and one of its reasons is testicular ischemic/ reperfusion (ir) injury. therefore the present study aims at producing new drugs for the treatment of testicular ir injury. methods: 42 an...

Bioavailability of flavonoids is low, especially when occurring as rhamnoglucosides. Thus, the hydrolysis of rutin, hesperidin, naringin and a mixture of narcissin and rutin (from Cyrtosperma johnstonii) by 14 selected probiotics was tested. All strains showed rhamnosidase activity as shown using 4-nitrophenyl α-L-rhamnopyranoside as a substrate. Hesperidin was hydrolysed by 8-27% after 4 and u...