INTRODUCTION Nasopharyngeal carcinoma among the children has been rare accounting for only 1% of all pediatric malignancies. Both genetic and environmental factors have contributed to the development of nasopharyngeal carcinoma. Among the children there was a higher rate of undifferentiated histology. The mean age of nasopharyngeal carcinoma diagnosis has been 11 years old age; and the most com...

Anesthesiology, V 125 • No 3 596 September 2016 A double modified nasopharyngeal airway connected to a breathing circuit to assist ventilation could be a great rescue airway technique. This setup provides unobstructed spontaneous ventilation, end-tidal carbon dioxide monitoring, continuous positive airway pressure, and assisted ventilation as needed.1 A modif...

BACKGROUND Nasopharyngeal carcinoma with leptomeningeal involvement is rare and typically has poor prognosis. METHODS AND RESULTS We present a case report of a patient with nasopharyngeal carcinoma who was treated with high-dose intravenous methotrexate and remains asymptomatic and without clinical evidence of disease 6 years later. CONCLUSIONS Systemic high-dose methotrexate should be eval...

BACKGROUND & OBJECTIVES Haemophilus influenzae is an important cause of mortality and morbidity among young children in developing countries. Increasing incidence of antibiotic resistance especially production of extended spectrum beta lactamase (ESBL) has made treatment and management of H. influenzae infection more difficult. Nasopharyngeal H. influenzae isolates are excellent surrogate for d...

Nasopharyngeal carcinoma is an uncommon head and neck malignancy which can rarely present with cranial nerve palsies. Here we report a case of nasopharyngeal mass presented initially ophthalmic complaints due to compression nerves in superior orbital fissure resulting Rochen-Duvigneaud syndrome. It was histologically proven as non keratinising differentiated type

no nasopharyngeal tumor was identified in 12 cases with adult OME that were reviewed.[8] Postnasal space examination is further necessitated by the fact that nasopharyngeal tumor is common in the third and fifth decades of life, at which stage most of our patients were. Nasopharyngeal tumors have been known to present with otological features of OME, in addition to nasal, neuro-ophthalmic and n...

BACKGROUND While almost all infants are infected with respiratory syncytial virus (RSV) before the age of 2 years, only a small percentage develops severe disease. Previous studies suggest that the nasopharyngeal microbiome affects disease development. We therefore studied the effect of the nasopharyngeal microbiome on viral load and mucosal cytokine responses, two important factors influencing...

TFAP2A is a transcription factor that orchestrates a variety of cell processes, including cell growth and tissue differentiation. However, the regulation of TFAP2A in human nasopharyngeal carcinoma tumorigenesis and its precise mechanism of action remain largely unknown. In this study, we investigated the biologic role and clinical significance of TFAP2A in nasopharyngeal carcinoma growth and p...