Methods for expressing a heteromeric taste receptor that responds to umami taste stimuli are provided. These methods comprise the co-expression of T1R1 and T1R3 nucleic acid sequences in a host cell that desirably also expresses a G protein that couples therewith, e.g., G.sub..alpha.15 and G.sub..alpha.16 or gustducin. In preferred embodiments, the host cells will be mammalian cells or Xenopus ...

Although most genes use RNA in the form of mRNA as a coding intermediate for protein production, there are many genes whose final products are RNA. These noncoding RNAs range from the familiar transfer and ribosomal RNAs to the more recently discovered regulatory RNAs. One type of regulatory RNA was first discovered during the study of nematode larval development. Two approximately 22nucleotide...

introduction: numerous studies have investigated the prevalence, incidence and clinical manifestations of gastrointestinal stromal tumors (gists). however, little is known about gists in iran. this pioneer study focuses on description of 36 patients with gists in iran. methods: a database was created for 36 patients suffering from gist who were treated in loghman medical center and tehran cance...

Term Used Definition Provided Source I/T strategy None provided Henderson and Venkatraman 1999 Information Management Strategy " A long-term precept for directing, implementing and supervising information management " (information management left undefined) Reponen 1994 (p. 30) " Deals with management of the entire information systems function, " referring to Earl (1989, p. 117): " the manageme...

The aim of this study was to determine the effect of knowledge management capabilities and information technology capabilities on innovative performance with the mediating role of organizational entrepreneurship, organizational learning and competitive advantage. The research method is descriptive-survey. The statistical population consists of all employees of Shimifar Iran Company, and 137 peo...

At least 40 QTL studies have been reported in pigs (Andersson et al., 1994 a,b; Andersson-Eklund et al., 1998; Beeckmann, 2000; Bidanel et al., 2001; Cassady et al., 2001; Casas-Carrillo et al, 1997; Ciobanu et al, 2001; De Koning et al., 1999; De Koning et al., 2000; De Koning et al., 2001a,b; Desautes et al., 2002; Edfors-Lilja et al., 1998; Geldermann et al., 1999; Grindflek et al., 2001; Ha...

Immunoprecipitation is a useful method for isolating proteins of interest from cellular extracts using specific antibodies. Following immunoprecipitation of a protein of interest, it can be determined via Western blot whether any other proteins have co-immunoprecipitated. This method has been routinely used over the past several decades to study protein–protein interactions and thereby elucidat...

Making scientific measurements can alter the subject of the measurement (Heisenberg 1927), limiting one’s ability to understand how systems operate when they are not being studied. The idea that such effects occur during ecological research is not new (e.g., Singer and Wedlake 1981, Major 1990, Duncan et al. 2002), but our recent studies have renewed awareness (Cahill et al. 2001, 2002, Hik et ...

Cervical dystonia is the most common form of focal dystonia (Dashtipour et al., 2007). It is characterized by involuntary movement of the neck resulting in abnormal neck posture (Brin & Benabou, 1999; Dent, 2002). Cervicalgia and headache sometimes occur in patients suffering from the disease (Albanese, 2005; Brashear, 2004, Schim, 2006). A critical long-term sequelae of this kind of movement d...