OF THE THESIS CONTROLLED-RELEASE ANTIMICROBIALS FOR PREVENTING BIOFILM FORMATION IN FOOD AND MEDICAL APPLICATIONS By LINDA E. ROSENBERG Thesis Director: Dr. Michael Chikindas Bacterial biofilms generally are more resistant to stresses as compared to free planktonic cells. Therefore, the discovery of antimicrobial stress factors that have strong inhibitory effects on bacterial biofilm formation ...

Antimicrobial substances may be synthetic, semisynthetic, or of natural origin (i.e., from plants and animals). Antimicrobials are considered "miracle drugs" and can determine if an infected patient/animal recovers or dies. However, the misuse of antimicrobials has led to the development of multi-drug-resistant bacteria, which is one of the greatest challenges for healthcare practitioners and i...

Disinfection is defined as the destruction of microorganisms, not necessarily destroy all microbes but may reducing them to an acceptable level. Thus, it could stop chain bugs transmission avoid infections. Antimicrobials are divided into antimicrobial agents and antibiotics. Disinfectants or hand sanitizers used prevent microbial contamination on inanimate objects that present in environment; ...

Lactobacillus species maintain the vaginal ecosystem in a healthy condition by production of antimicrobial substances. Depletion of lactobacilli in the vagina results in bacterial vaginosis (BV), where the normal flora is replaced by several bacterial pathogens, usually Gardnerella vaginalis and obligate anaerobes. BV may cause complications such as premature labor, low birth weight and increas...

Nowadays food preservation, quality maintenance, and safety are major growing concerns of the food industry. It is evident that over time consumers' demand for natural and safe food products with stringent regulations to prevent food-borne infectious diseases. Antimicrobial packaging which is thought to be a subset of active packaging and controlled release packaging is one such promising techn...

Citation: Dhakal D and Sohng JK (2015) Commentary: Toward a new focus in antibiotic and drug discovery from the Streptomyces arsenal. A commentary on Toward a new focus in antibiotic and drug discovery from the Streptomyces arsenal Infectious diseases caused by bacteria, particularly those gaining drug-resistance, are among the top causes of mortality in the world (Overbye and Barrett, 2005). T...

Antibiotics are developed to kill microorganisms; however, microorganisms develop and disseminate resistance as a reaction to antimicrobials in accordance with the laws of evolution and natural selection. Resistant and multidrug-resistant bacterial infections comprise a great problem in both the community and hospital setting. Increasing values of health expenditures, including antibiotics, is ...

  Objective(s):   The ongoing increasing antibiotic resistance is one of the biggest challenges faced by global public health. The perennial need for new antimicrobials against a background of increasing antibiotic resistance in pathogenic and opportunistic microorganisms obliges the scientific community to constantly develop new drugs and antimicrobial agents. Lichens are known pro...

AIMS This study examined 448 Campylobacter strains isolated in 1999 and 2000 from US feedlot cattle for resistance to 12 antimicrobials. METHODS AND RESULTS Isolates were tested for antimicrobial susceptibility using the E-test method. Approximately 60% (n = 267) were resistant to one or more antimicrobials, and 19.6% (n = 88) were resistant to two or more antimicrobials. Of the Campylobacter...