Neuronal survival in multiple sclerosis (MS) and other demyelinating diseases depends on the preservation of myelin and remyelination of axons. Myelin protection is the main purpose to decrease myelin damage in the central nervous system (CNS). Ursolic acid (UA) as a natural product in apple is suggested to protect neural cells. This study is the first to demonstrate an effect for UA on CNS mye...

In the microenvironment concept of avian botulism epizootiology, it is hypothesized that invertebrate carcasses may serve both as a substrate for toxin production by Clostridium botulinum type C and as a vehicle for toxin transmission to water birds. We field-tested that hypothesis by attempting to induce botulism in wing-clipped mallard ducks (Anas platyrhynchos) on sewage oxidation ponds in U...

The steroidal neurotoxin (-)-batrachotoxin functions as a potent agonist of voltage-gated sodium ion channels (NaVs). Here we report concise asymmetric syntheses of the natural (-) and non-natural (+) antipodes of batrachotoxin, as well both enantiomers of a C-20 benzoate-modified derivative. Electrophysiological characterization of these molecules against NaV subtypes establishes the non-natur...

Neuronal survival in multiple sclerosis (MS) and other demyelinating diseases depends on the preservation of myelin and remyelination of axons. Myelin protection is the main purpose to decrease myelin damage in the central nervous system (CNS). Ursolic acid (UA) as a natural product in apple is suggested to protect neural cells. This study is the first to demonstrate an effect for UA on CNS mye...

background: this cross sectional study was conducted to evaluate the effect of &gamma-rays; and electron-beam irradiation with a commercial toxin binder-milbond-tx on the performance, feed components, and meat quality of japanese quails challenged with aflatoxin b1. methods: overall, 168 one-d-old chicks (japanese quails) were allocated to eight treatments with three replicates based on a compl...

abstract how to cite this article: eryılmaz a, başal y, günel c, ozkul a, tosun a. successful treatment of essential palatal tremor lasting over a long term with a rare application of botulinum toxin in a child. iran j child neurol. autumn 2015;9(4): 75-77. abstract objective attention deficit hyperactivity disorder (adhd) is one of the most prevalent mental health disorders. in recent years, t...

purpose : recession is the main surgical procedure in correction of eye deviation in duane’s syndrome. we evaluate the efficacy of botulinum toxin injection in the treatment of this type of strabismus instead of surgery or before it. methods : three patients with duane’s syndrome type i and one patient with type ii were selected at poostchi eye clinic from patients who diagnosed primarily and h...