Background and Objectives: Negative symptoms emerge in many patients with psychotic disorders long before the onset of the acute illness. These symptoms are often impossible to differentiate from certain Cluster A personality traits. Methods: The current study examines the extent to which premorbid negative symptoms are contributing factors to the development of primary and secondary negative s...

RESUMEN Antecedentes: se ha planteado la hipótesis de que los pacientes con esquizofrenia emplean la nicotina para reducir los síntomas negativos de su enfermedad y para mejorar su función cognitiva; sin embargo, no existe evidencia concluyente en la literatura sobre el vínculo entre el consumo de nicotina y la disminución de los síntomas negativos de la enfermedad. Objetivo: investigar los efe...

Persistent negative symptoms represent an alternative approach for assessing negative symptoms in the context of clinical trials. Persistent negative symptoms are designed to capture those symptoms that lead to functional impairment but are currently understudied and for which there are no currently available effective treatments. Persistent negative symptoms differ from the 2 most commonly use...

Interest in the negative symptoms of schizophrenia has increased rapidly over the last several decades, paralleling a growing interest in functional, in addition to clinical, recovery, and evidence underscoring the importance negative symptoms play in the former. Efforts continue to better define and measure negative symptoms, distinguish their impact from that of other symptom domains, and est...

objective : poor premorbid adjustment has been reported to be a predictor of more severe psychotic symptoms and poor quality of life in such psychotic disorders  as  schizophrenia.  however,  most  studies  were  performed  on chronic schizophrenic patients, and proposed the likelihood of recall biases and the effect of chronicity.  the aim of this study was to investigate these factors in a sa...

This study investigated the possible relationship between negative processing biases and subsequent depression. The Scrambled Sentences Test (SST), a measure of processing bias, was administered to a large sample of undergraduates. Participants also completed self-report measures of thought suppression tendencies, current level of depression, and lifetime worst-depression symptoms. High scores ...

We report five cases of treatment-resistant schizophrenia that presented with prominent negative and positive symptoms. They fulfill the criteria of diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5). They showed lack of response despite receiving multiple trials of first and second generation psychotropic agents. We decided ...

The tendency to generalize from a single failure to one's entire self-worth is an important correlate and predictor of depression. Despite conceptual overlap between cognitive biases in anxiety and depression, little research has examined whether negative generalization relates to anxiety symptoms. We examined associations of negative generalization with symptoms of several anxiety disorders, a...

Thirty four cases of endogenous major depression (RDC) have been studied in order to examine whether negative symptoms influence the outcome of depression, by comparing depressives with and without predominant negative symptoms, and by examining which negative symptoms have high percentage reduction in scores. Patients were rated on Scale for Assessment of Negative Symptoms (SANS) during their ...

This study examines the differences between the prevalence of negative symptoms in schizophrenia and Major depression, diagnosed according to RDC, using Andreasen's Scale for Assessment of Negative Symptoms, SANS. Global ratings of affective flattening, alogia, avolition and inattention were significantly higher in schizophrenics whereas anhedonia - asociality were seen as commonly in depressiv...