نتایج جستجو برای: nephroprotective activity

تعداد نتایج: 1134807  

2013
Ganiyu Oboh Ayodele J. Akinyemi Adedayo O. Ademiluyi

Allium sativum have been an important food ingredient in the management or treatment of renal disease. Therefore, this study sought to determine the inhibitory effect of phenolic-rich extract from A. sativum on angiotensin 1 converting enzyme (ACE) activity (key enzyme linked to renal dysfunction) and cisplatin-induced lipid peroxidation in rat kidney in vitro. The free phenolics were extracted...

Journal: :Journal of Nephrology & Therapeutics 2016

Journal: :Antimicrobial agents and chemotherapy 1993
S K Swan D N Gilbert S J Kohlhepp P W Kohnen W M Bennett

Polyaspartic acid (PAA) ameliorates experimental gentamicin nephrotoxicity despite marked accumulation of gentamicin in the renal cortex. The experiments described here probe the extent of PAA's nephroprotective action when increasing doses of gentamicin, in excess of an established nephrotoxic dose (40 mg/kg of body weight per day), are administered. After 10 days, virtually complete nephropro...

Journal: :Iranian journal of kidney diseases 2012
Eric L Yarnell

Herbal medicines are being used with greater frequency by practitioners of natural medicine in the United States. Many categories of herbs are used, primarily angiotensin antagonists, nonspecific nephroprotective, and immunomodulating/adaptogenic herbs. The most common herbs in each category are discussed both from a historical and scientific perspective. For the first time, a case series of th...

Journal: :Diabetes 2015
Gilberto Velho Stéphanie Ragot Kamel Mohammedi Elise Gand Mathilde Fraty Frédéric Fumeron Pierre-Jean Saulnier Naima Bellili-Munoz Nadine Bouby Louis Potier François Alhenc-Gelas Michel Marre Samy Hadjadj Ronan Roussel

Production of adrenomedullin (ADM), a vasodilator peptide, increases in response to ischemia and hypoxia in the vascular wall and the kidney. This may be an adaptive response providing protection against organ damage. We investigated the hypothesis that ADM has a nephroprotective effect in two prospective cohorts of patients with type 2 diabetes recruited in France. The highest tertile of plasm...

2012
Viviane Gomes Portella Gustavo Pereira Cosenza Lúcio Ricardo Leite Diniz Lílian Fernanda Pacheco Giovanni Dantas Cassali Marcelo Vidigal Caliari Maria das Graças Lins Brandão Maria Aparecida Ribeiro Vieira

BACKGROUND/AIMS Leaves of Echinodorus macrophyllus (EM), from the Alismataceae family, have been used in Brazilian folk medicine for their anti-inflammatory and diuretic properties. In this work, the diuretic and nephroprotective activities of crude extracts of EM were evaluated. METHODS Normal Wistar rats were given 0.9% NaCl containing either EM (10-300 mg/kg), furosemide (13 mg/kg) or argi...

2016
Inayat U Rahman Mohammad Bashir Khalil Ur Rahman

Protection against diabetic nephropathy (DN) is one of the main targets in diabetes treatment and present study evaluates the nephroprotective effect of Carica papaya L. in streptozotocin (STZ) induced diabetic rats. DN rats were treated with 1.5 and 2.5 gm/dl C. papaya leaf extract for 6 weeks to determine its nephroprotective effect with different parameters. Pimagedine (1 ml/mg) served as a ...

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