نتایج جستجو برای: nephroprotective activity
تعداد نتایج: 1134807 فیلتر نتایج به سال:
Allium sativum have been an important food ingredient in the management or treatment of renal disease. Therefore, this study sought to determine the inhibitory effect of phenolic-rich extract from A. sativum on angiotensin 1 converting enzyme (ACE) activity (key enzyme linked to renal dysfunction) and cisplatin-induced lipid peroxidation in rat kidney in vitro. The free phenolics were extracted...
Polyaspartic acid (PAA) ameliorates experimental gentamicin nephrotoxicity despite marked accumulation of gentamicin in the renal cortex. The experiments described here probe the extent of PAA's nephroprotective action when increasing doses of gentamicin, in excess of an established nephrotoxic dose (40 mg/kg of body weight per day), are administered. After 10 days, virtually complete nephropro...
Herbal medicines are being used with greater frequency by practitioners of natural medicine in the United States. Many categories of herbs are used, primarily angiotensin antagonists, nonspecific nephroprotective, and immunomodulating/adaptogenic herbs. The most common herbs in each category are discussed both from a historical and scientific perspective. For the first time, a case series of th...
Production of adrenomedullin (ADM), a vasodilator peptide, increases in response to ischemia and hypoxia in the vascular wall and the kidney. This may be an adaptive response providing protection against organ damage. We investigated the hypothesis that ADM has a nephroprotective effect in two prospective cohorts of patients with type 2 diabetes recruited in France. The highest tertile of plasm...
BACKGROUND/AIMS Leaves of Echinodorus macrophyllus (EM), from the Alismataceae family, have been used in Brazilian folk medicine for their anti-inflammatory and diuretic properties. In this work, the diuretic and nephroprotective activities of crude extracts of EM were evaluated. METHODS Normal Wistar rats were given 0.9% NaCl containing either EM (10-300 mg/kg), furosemide (13 mg/kg) or argi...
Protection against diabetic nephropathy (DN) is one of the main targets in diabetes treatment and present study evaluates the nephroprotective effect of Carica papaya L. in streptozotocin (STZ) induced diabetic rats. DN rats were treated with 1.5 and 2.5 gm/dl C. papaya leaf extract for 6 weeks to determine its nephroprotective effect with different parameters. Pimagedine (1 ml/mg) served as a ...
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