Measurement of peripheral nerve conduction in man dates back to von HelmhQltz ( 1:' . Ili) and now forms a part of routine clinical examination in various neuropathic conditions. Prominent in this group is leprosy, but it is surprising to note in an editorial by Wade ( 18) that as late as 1954 sufficient information on the conduction velocity of peripheral nerves in leprosy was not available. I...

We studied variation in peripheral nerve conduction velocity (PNCV) and intelligence in a group of 16-year-old Dutch twins. It has been suggested that both brain nerve conduction velocity and PNCV are positively correlated with intelligence (Reed, 1984) and that heritable differences in NCV may explain part of the well established heritability of intelligence. The Standard Progressive Matrices ...

This study explores in detail the functional consequences of subtle retraction and detachment of myelin around the nodes of Ranvier following mild-to-moderate crush or stretch mediated injury. An equivalent electrical circuit model for a series of equally spaced nodes of Ranvier was created incorporating extracellular and axonal resistances, paranodal resistances, nodal capacitances, time varyi...

Near normal glucoregulation was maintained in 10 patients with insulin-dependent (type I) diabetes mellitus for 6 wk with preprogrammed continuous subcutaneous insulin infusion using a portable battery-powered infusion pump (CSII). This form of therapy resulted in a statistically significant increase in motor nerve conduction velocity in the median and peroneal nerves compared with baseline val...

PURPOSE To determine the diagnostic utility of waveform analysis of compound muscle action potentials (CMAP) for carpal tunnel syndrome (CTS). METHODS A total of 131 hands in 71 patients diagnosed with CTS (grouped according to severity) and 80 hands in 44 normal subjects were evaluated using nerve conduction test through the carpal tunnel combined with waveform analysis of CMAP. RESULTS Co...

A 24-year old female patient with the history of pressure ulcers in distal extremities resulted in severe deformity will be reported. Her disease started when she was 9 years old and a similar history was found in her brother. In physical examination, pain and temperature sensations were impaired in distal extremities. Nerve conduction velocity showed impaired sensory and normal motor responses...

Rat sciatic nerve fibres do not conduct nerve impulses at a normal rate after the rat has been injected with alloxan (Eliasson, 1964). The dose given to the rat must be large enough to cause clinically detectable diabetes. The conduction rate slows to levels of 30 to 50% of the original within the first 10 days after the injection; possibly this is due to a direct toxic effect of the alloxan on...

Since Merrit and Putnam (1938) 8 introduced the diphenylhydantoin (DPH) in the treatment of epilepsy, it has been used largely as the main drug in many forms of the disease. Several attempts have been made to demonstrate its action on the peri­ pheral nerve, but the obtained results are controversial. Korey 6 first, and Morrell, Bradley and Ptashne after, gave experimental evidence of DPH toxic...

OBJECTIVES To establish a sound objective model for assessing the effects of neurotrophic factors on facial nerve function after injury and to compare the effects of brain-derived neurotrophic factor (BDNF) with its neutralizing antibody on facial nerve function after injury. DESIGN Prospective electrophysiologic analysis of recovery of function 4 weeks after axotomy involving facial nerve tr...

185 www.ijbamr.com “Effect of human occupational exposure to organic solvents: An Electrophysiological Study.” *Reshu gupta **Abhishek Kawatra, ***K C Mathur , #BK Binawara, ##Rajniesh Sharma ^ Arvind Vyas ..................................................................................................................................... ABSTRACT: Introduction: Exposure to solvents is ubiquitou...