linated nerve fibers and Schwann cells is found near blood capillaries in the lamina propria of the proventricular mucosa of the finch. At least two types of endocrine cells (type I and II) are present mainly in the lamina propria mucosae where they form a neuro-endocrine complex, but some cells of both types are also seen in the basal part of the epithelial layer like mammalian basal-granulate...

A simple and reliable radioimmunoassay has been developed for a new gut hormone, HPP. In the primate 93% of the total PP was found in the pancreas with a small amount throughout the remaining gastrointestinal tract. HPP has been shown to be produced by a number of pancreatic apudomas and their metastases. The immunoreactive PP from these tumours and from normal pancreas was chromatographically ...

Five patients with metastatic pancreatic endocrine tumours injected a long acting somatostatin analogue (SMS 201-995) 50 micrograms subcutaneously every 12 hours and were followed up for three to six months. Treatment aimed at controlling excess secretion of hormone by the tumours thereby bringing symptomatic relief. Four patients showed a significant reduction in tumour related hormone concent...

During the past 10 years there has been particular interest in the occurrence of a number of endocrine syndromes in association with tumours of organs other than the endocrines. Evidence is increasing to suggest that these result from the formation of hormone-like substances by the tumours. The clinical importance and theoretical implications of these syndromes constitute the justification for ...

Current studies try to demonstrate a tight correlation between the endocrine and the neuropsychiatric physiopathology by a total different approach of the common pathology supporting an essential link between the neuro-hormonal mechanisms triggering the disorders from the depressive sphere and those from the scope of the crude hypothyroidism and of the serious forms. The medicines interaction b...