Background Immunotherapy with T cells or bispecific T cell engagers is one promising approach to improve outcomes for patients with CD19-positive hematological malignancies. We had previously shown that T cells expressing bispecific T cell engagers that recognize CD19 and CD3 (CD19-ENG T cells) are activated in an antigen dependent manner, recruit resident T cells to tumors, and have anti-tumor...

Domestic abuse affects people of every race, class, age, and nation. There is significant research on the prevalence and effects of domestic abuse; however, such research typically involves population-based surveys that have high financial costs. This work provides a qualitative analysis of domestic abuse using data collected from the social and news-aggregation website reddit.com. We develop c...

Depending on the news source, a reader can be exposed to a different narrative and conflicting perceptions for the same event. Today, news aggregators help users cope with the large volume of news published daily. However, aggregators focus on presenting shared information, but do not expose the different perspectives from articles on same topics. Thus, users of such aggregators suffer from med...

Emerging within Systemic Linguistics, Appraisal/Evaluation is a framework for analyzing the language of evaluation, providing techniques for the systematic analysis of evaluation and stance as they operate in whole texts and in groupings of texts. There are three systems in the Appraisal framework: Attitude, Engagement, and Graduation. This study sets out to analyze the use of the system of Eng...

contrastive rhetorical analysis as a way of understanding different ways through which writers from various cultural backgrounds shape their discourse was officially initiated by the works of kaplan (1966). this study tries to use the methodology to investigate the news reports in two american and iranian widely published newspapers. using the analytical methodologies of contrastive rhetoric an...