نتایج جستجو برای: nissle 1917

تعداد نتایج: 5261  

Journal: :European journal of immunology 2010
Emmanuelle Adam Laurence Delbrassine Céline Bouillot Virginie Reynders Anne-Catherine Mailleux Eric Muraille Alain Jacquet

Experimental animal and human studies have demonstrated that probiotic strains have beneficial effects on allergy. Here we report that the probiotic Escherichia coli Nissle 1917 strain (EcN) is able to activate DC, as shown by important cytokine synthesis together with up-regulation of membrane expression of CD40, CD80 and CD86. This EcN-induced DC activation was strictly dependent on the TLR4 ...

2015
Jonathan Nzakizwanayo Cinzia Dedi Guy Standen Wendy M. Macfarlane Bhavik A. Patel Brian V. Jones

Accumulating evidence shows indigenous gut microbes can interact with the human host through modulation of serotonin (5-HT) signaling. Here we investigate the impact of the probiotic Escherichia coli Nissle 1917 (EcN) on 5-HT signalling in gut tissues. Ex-vivo mouse ileal tissue sections were treated with either EcN or the human gut commensal MG1655, and effects on levels of 5-HT, precursors, a...

2016
Artur Dembiński Zygmunt Warzecha Piotr Ceranowicz Marcin Dembiński Jakub Cieszkowski Tomasz Gosiewski Małgorzata Bulanda Beata Kuśnierz-Cabala Krystyna Gałązka Peter Christopher Konturek

Background. Inflammatory bowel disease results from the dysregulation of immune response to environmental and microbial agents in genetically susceptible individuals. The aim of the present study was to examine the effect of rifaximin and/or Mutaflor (Escherichia coli Nissle 1917, EcN) administration on the healing of acetic acid-induced colitis. Methods. Colitis was induced in male Wistar rats...

2013
Olga Revelles Pierre Millard Jean-Philippe Nougayrède Ulrich Dobrindt Eric Oswald Fabien Létisse Jean-Charles Portais

The role of the post-transcriptional carbon storage regulator (Csr) system in nutrient utilization and in the control of the central metabolism in E. coli reference commensal strain Nissle 1917 was investigated. Analysis of the growth capabilities of mutants altered for various components of the Csr system (csrA51, csrB, csrC and csrD mutations) showed that only the protein CsrA - the key compo...

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