[figure: see text] Monomer (R,R)-3-aza-3-(p-vinylbenzyl)-1,5-diphenyl-1,5-dihydroxypentane (2) when polymerized with styrene and divinylbenzene affords polymers, onto which lithium and aluminum are incorporated via reaction with lithium aluminum hydride. The resulting insoluble polymers containing chiral lithium and aluminum active centers are quite effective for asymmetric Michael addition of ...

2.1.Date of QMRF: 21.08.2009 2.2.QMRF author(s) and contact details: [1]Indrek Tulp Molcode Ltd. Turu 2, Tartu, 51014, Estonia [email protected] http://www.molcode.com [2]Tarmo Tamm Molcode Ltd. Turu 2, Tartu, 51014, Estonia [email protected] http://www.molcode.com [3]Gunnar Karelson Molcode Ltd. Turu 2, Tartu, 51014, Estonia [email protected] http://www.molcode.com [4]Dimitar Dobchev Molcod...

Hydroxytriazenes behave like bidentate ligands which have alpha hydroxyl group relative to azo group. The synthesis includes reduction of an alkyl or aryl nitro compound in neutral medium to get hydroxylamine and diazotization of an aromatic amine to get diazonium chloride. When these two that is hydroxylamine and respective diazonium salt are coupled we get hydroxytriazene as a product. A gene...

SYNTHESIS 2006, No. 19, pp 3316–3340xx.xx.2006 Advanced online publication: 06.09.2006 DOI: 10.1055/s-2006-950231; Art ID: C04506SS © Georg Thieme Verlag Stuttgart · New York Abstract: A combination of palladium(II) acetate, aqueous potassium fluoride, and polymethylhydrosiloxane (PMHS) facilitates the room-temperature reduction of aromatic nitro compounds to anilines. These reactions tend to b...

Selective and rapid reductLon of nitro compounds is still area of considerable synthetic interestl, particularly when a molecule has several other reducible moieties. Numerous new reagents*-l4 have been developed for reduction of aromatic nitro compounds, however little attention has been paid to the reduction of aliphatic nitro compound&ry,S, which are traditionally reduced by high pressure ca...

Novel tetrasubstituted pyrazole derivatives bearing a nitro substituent on their A-phenol ring were synthesized and their binding affinity towards the estrogen receptor (ER) subtypes ERalpha and ERbeta was determined. Among compounds tested, the 2-nitrophenol derivative 5c was found to bind satisfactorily to both estrogen receptor subtypes (RBAalpha=5.17 and RBAbeta=3.27). In general, the intro...