Limitation of different nutrients in Streptomyces coelicolor A3(2) triggers nutrient-stress responses, mediated by PhoP, GlnR, AfsR and other regulators, that are integrated at the molecular level and control secondary metabolite biosynthesis and differentiation. In addition, utilization of chitin or N-acetylglucosamine regulates secondary metabolite biosynthesis by a mechanism mediated by DasR...

Stable isotope tracing is a powerful method for interrogating metabolic enzyme activities across the metabolic network of living cells. However, most studies of mammalian cells have used (13)C-labeled tracers only and focused on reactions in central carbon metabolism. Cellular metabolism, however, involves other biologically important elements, including nitrogen, hydrogen, oxygen, phosphate an...

I. Studies were made with pair-fed vitamin Blz-deficient and vitamin B12-treated or cobalt-treated ewes fed a Co-deficient diet in cages. Measurements were made of body-weight changes and some observations were made of energy and nitrogen metabolism. The effects of oral Co on energy and nitrogen metabolism were examined in sheep fed the Co-deficient diet, but not yet deficient of vitamin B,, in...

In 1950 Dresel and Moyle published a paper concerning the nitrogenous excretion of amphipods and isopods, upon which most subsequent authors of text-books have relied when discussing protein metabolism and nitrogen excretion in these groups of animals (Prosser & Brown, 1961; Lockwood, 1963). The major findings by Dresel & Moyle pertinent to our discussion were the following: (1) Isopods are pre...

AMT1-3 encodes the high affinity NH₄⁺ transporter in rice roots and is predominantly expressed under nitrogen starvation. In order to evaluate the effect of AMT1-3 gene on rice growth, nitrogen absorption and metabolism, we generated AMT1-3-overexpressing plants and analyzed the growth phenotype, yield, carbon and nitrogen metabolic status, and gene expression profiles. Although AMT1-3 mRNA acc...

The effect of feeding chopped and unchopped groundnut haulm (Harawa) on nutrient intake, metabolism utilization was determined in 24 (12 each male female) growing Yankasa lambs. Feeding harawa significantly (P 0.05) Increased feed the digestibility nutrients liveweight gains. It also had an ap­preciable nitrogen retention pro­duction total rumen nitrogen, ammonia-nitrogen volatile fatty acids. ...

Growth of Pseudomonas AT3 on the alkaloid atropine as its sole source of carbon and nitrogen is nitrogen-limited and proceeds by degradation of the tropic acid part of the molecule, with the metabolism of the tropine being limited to the point of release of its nitrogen. A nitrogen-free compound accumulated in the growth medium and was isolated and identified as 6-hydroxycyclohepta-1,4-dione. T...