Background: Plasmapheresis is a well-recognised method for harvestingplasma.  It was introduced in the 1950s and is currently employed worldwide.  This method has been in use in Iran since 1979. Objective: To evaluate the efficacy of donor safety program used at the Iranian Blood Transfusion Organization. Methods: A comparison is made of the protein concentrations between the first-time and lon...

background: plasmapheresis is a well-recognised method for harvestingplasma.  it was introduced in the 1950s and is currently employed worldwide.  this method has been in use in iran since 1979.   objective: to evaluate the efficacy of donor safety program used at the iranian blood transfusion organization.   methods: a comparison is made of the protein concentrations between the first-time and...

protein secretory systems are found in all living organisms including gram negative bacteria, and eukaryotic cell’s organelles that are derived from these bacteria. unlike all other living organisms, gram negative bacteria have different protein secretory systems. at least there are four different independent secretory systems, which are responsible to transport the secreted proteins to the mil...

We report a novel fusion tag for expressing recombinant proteins in E. coli. The fusion tag is the C-terminus part of the human GMCSF gene comprising 45 amino acids, which aid in over expression of otherwise non expressible genes. Expression of hIFN 2b with this fusion tag also escapes the requirement of rare codons for expression. This is also a first report of a small fusion tag of human orig...

There are two general types of metabolism experiments: those of relatively short duration covering several periods, each from a few days to a week in length; and those carried out over as long a period as possible. As examples of the first type we have such investigations as the study of the effect of a given substance upon the nitrogenous equilibrium, or the study of the ability of the animal ...

Membrane-binding properties of human and bovine forms of vitamin K-dependent proteins Z, S, and C were characterized. Each of these proteins showed unique properties and interspecies differences that correlated with specific amino acid sequence variations in the amino-terminal 45 residues. Protein Z showed 100-fold slower membrane binding and dissociation kinetics relative to other vitamin K-de...