Coaptation characteristics are crucial in an assessment of the competence reconstructed aortic valves. Shell or membrane formulations can be used to model valve cusps coaptation. In this paper we compare both terms their coaptation for first time. Our numerical thin shell is based on a combination hyperelastic nodal forces method and rotation-free finite elements. The verified several popular b...

Atrioventricular Nodal Reentry Tachycardia (AVNRT) ablation is a common procedure in contemporary electrophysiology practice. Traditionally for AVNRT has been performed with non-irrigated catheters, guided by fluoroscopy and intracardiac electrograms. Increasingly electroanatomic mapping systems are utilized to allow low or zero procedures. Contact force catheters can provide information on tis...

Nodal is a TGF-β-related embryonic morphogen that is expressed in multiple human cancers. Detection of Nodal expression in these tissues can be challenging if issues related to Nodal transcription and protein processing are not considered. Here, we discuss certain characteristics related to Nodal expression and function and how these can facilitate acquisition and interpretation of expression d...

Nodal signals belong to the TGF-beta superfamily and are essential for the induction of mesoderm and endoderm and the determination of the left-right axis. Nodal signals can act as morphogens-they have concentration-dependent effects and can act at a distance from their source of production. Nodal and its feedback inhibitor Lefty form an activator/inhibitor pair that behaves similarly to postul...

In vertebrates, left-right (LR) axis specification is determined by a ciliated structure in the posterior region of the embryo. Fluid flow in this ciliated structure is responsible for the induction of unilateral left-sided Nodal activity in the lateral plate mesoderm, which in turn regulates organ laterality. Bmp signalling activity has been implied in repressing Nodal expression on the right ...

BACKGROUND AND AIMS Cereals have two root systems. The primary system originates from the embryo when the seed germinates and can support the plant until it produces grain. The nodal system can emerge from stem nodes throughout the plant's life; its value for yield is unclear and depends on the environment. The aim of this study was to test the role of nodal roots of sorghum and millet in plant...

The mechanisms that govern node of Ranvier organization, stability, and long-term maintenance remain to be fully elucidated. One of the molecular components of the node is the cytoskeletal scaffolding protein, ankyrin G (AnkG), which interacts with multiple members of the nodal complex. The role of AnkG in nodal organization and maintenance is still not clearly defined as to whether AnkG functi...