BACKGROUND The dermoscopic criteria of extrafacial melanomas are well-known. OBJECTIVE To determine the frequency of dermatoscopic findings in head and neck melanomas (HNM) and to assess the distinguishing dermoscopic criteria of facial and extrafacial melanoma. METHODS This observational study included 108 patients with HNM (63% male, mean age 64 years). Participants underwent individual d...

As Mr. V., a 52-year-old male, was getting his hair cut, his barber noticed a dark bump in an area on the side of his scalp, where the hair was thinning. At Mr. V.’s next haircut, his barber indicated that the area was getting larger and that it looked like it had bled. Mr. V. made an appointment with his primary care doctor, who then sent Mr. V. to a dermatologist. The dermatologist biopsied t...

BACKGROUND Melanoma is a deadly disease affecting people worldwide. Genetic studies have identified different melanoma subtypes characterized by specific recurrently mutated genes and led to the successful clinical introduction of targeted therapies. Hotspot mutations in SF3B1 were recently reported in uveal melanoma. Our aim was to see if these mutations also occur in cutaneous melanoma. FIN...

Vulvar melanomas are rare, with incidence rates in the range of 0.1–0.19 per 1000,000 women. In India, due to less reporting and late onset, only a few cases are reported. They account for 4–10 % of all cases and are the second most common form of vulvar malignancy after squamous cell carcinoma. Mean age of the occurrence is 69 years (most common in 60–70 years). Also, 5 years’ survival is rare...

BACKGROUND The incidence of nodular melanoma (NM) has been consistently described as at least 10-15% of total melanomas for over 15 years despite advances in diagnostic algorithms and medical technology. NMs are strongly correlated with faster rates of growth and poorer prognosis and thus provide clinicians with a challenge for early recognition. OBJECTIVE To evaluate diagnostic clues of cons...

New Zealand Maori, Pacific, and Asian people develop melanoma less frequently than New Zealand Europeans, but little is known about melanomas that develop in these people. We examined the characteristics of melanoma in these minority ethnic groups in New Zealand. In 2007, all first primary melanomas diagnosed from January 1996 to December 2006 were extracted from the New Zealand Cancer Registry...

Melanoma is one of the most malignant skin tumors with constantly rising incidence worldwide, especially in fair-skinned populations. Melanoma is usually diagnosed at the average age 50, but, nowadays is also diagnosed more frequently in younger adults, and very rarely in childhood. There is no unique or specific clinical presentation of a melanoma. The clinical presentation of melanomas varies...

BACKGROUND Genetic alterations have been identified in melanomas according to different levels of sun exposure. Whereas the conventional morphology-based classification provides a clue for tumor growth and prognosis, the new classification by genetic alterations offers a basis for targeted therapy. OBJECTIVE The purpose of this study is to demonstrate the biological behavior of melanoma subty...

AIM To explore whether disparities exist in melanoma incidence and prognosis between White Hispanics and White non-Hispanics. METHODS Analyses were based on 42,770 patients with malignant melanoma in the United States, 2004 through 2006. RESULTS Hispanics were significantly less likely to be diagnosed with superficial spreading melanoma or Hutchinson's melanotic freckle, but significantly m...

A previous work concerning tumor control and skin damage in cutaneous melanoma treatments with BNCT has been extended to include doses, volumes and responses of 104 subcutaneous lesions from all patients treated in Argentina. Acute skin reactions were also scored for these patients, and cumulative dose-area histograms and dose-based figures of merit for skin were calculated. Broadening the tumo...