BACKGROUND Chromosomal fragile sites are heritable specific loci especially prone to breakage. Some of them are associated with human genetic disorders and several studies have demonstrated their importance in genome instability in cancer. MicroRNAs (miRNAs) are small non-coding RNAs responsible of post-transcriptional gene regulation and their involvement in several diseases such as cancer has...

The aim of the paper is to present the Delta 20 Fragility-Rings plot and its use for robustness-fragility analysis of proportional integral (PI) and proportional integral derivative (PID) controllers. Using the Delta 20 Fragility Index and the Nyquist plot it shows the areas on the L(jω) plane corresponding to robustness-fragile, robustness-non-fragile and robustnessresilient controllers provid...

In this paper, the problem of non-fragile finite-time stabilization for linear discrete mean-field stochastic systems is studied. The uncertain characteristics in control parameters are assumed to be random satisfying Bernoulli distribution. A new approach called “state transition matrix method” introduced and some necessary sufficient conditions derived solve underlying problem. Lyapunov theor...

In this paper we present an approach to design the non-fragile H controller for active vehicle suspensions. A quarter-car model with active suspension system is considered in this paper. By suitably formulating the sprung mass acceleration, suspension deflection and tire deflection as the optimization object and considering a priori norm-bounded controller gain variations, the non-fragile state...