OBJECTIVE The study aimed to validate the efficacy of detection of fetal cell-free DNA in maternal plasma of trisomy 21, 18 and 13 in a clinical setting. METHODS A total of 2340 women at high risk for Down syndrome based on maternal age, prenatal history or a positive sesum or sonographic screening test were offered prenatal noninvasive aneuploidy test. According to the prenatal noninvasive a...

A large amount of data has accumulated during the past 20 years demonstrating the value of exercise or pharmacologic stress planar and single-photon emission-computed tomographic (SPECT) perfusion imaging for risk stratification and prognostication in patients with suspected or known coronary artery disease (CAD) (1–14). The major goal of such noninvasive risk assessment is the identification o...

introduction: it is known that acute and chronic stress induce hormonal and neuronal changes which affecting both pain threshold and nociceptive behaviours. orexin plays an important role in modulation of pain and stress. considering pain modulation during stress and the role of orexin in pain and stress, orexin might be involved in pain modulation during stress.we evaluated the involvement of ...

introduction fetal movement started at the 7th weeks of pregnancy and by the end of pregnancy will gradually be perfect and harmonious. near-term fetuses can discriminate acoustic features, such as frequencies and spectra, and process complex auditory streams. in this study, we aimed to evaluate fatal movement in response to music and vibration stimulation. materials and methods this study is a...

in the hot compression test friction has a detrimental influence on the flow stress through the process and therefore, correcting the deformation curve for real behavior is very important for both researchers and engineers. in this study, a series of compression tests were simulated using abaqus software. in this study, it has been employed the taguchi method to design experiments by the factor...

INTRODUCTION Salivary biomarkers are suggested to provide a reliable, noninvasive and objective measurement of chronic psychosocial stress and helps in assessment of pivotal role of stress in causation or precipitation of multitude of health problems. OBJECTIVES To evaluate the usefulness of salivary alpha amylase activity as an objective indicator of chronic stress and to find out any correl...

Stress echocardiography is the combination of 2D echocardiography with a physical, pharmacological or electrical stress. The diagnostic end point for the detection of myocardial ischemia is the induction of a transient worsening in regional function during stress. Stress echocardiography provides similar diagnostic and prognostic accuracy as radionuclide stress perfusion imaging, but at a subst...

Echocardiography is the most widely used noninvasive test for assessing the structure and function of the heart, accounting for 14% of overall Medicare expenditures for imaging in 2007.1 Despite the availability of a variety of validated quantitative methods for assessing chamber size and cardiac function, many elements of echocardiographic interpretation remain qualitative rather than quantita...