Disease severity varies among cystic fibrosis (CF) patients carrying the same cystic fibrosis transmembrane conductance regulator (CFTR) genotype and among organs of the same individual. It has been shown that the class V splicing mutation 3849 + 10 kb C--> T produces both normal and aberrantly spliced CFTR transcripts. We analyzed the levels of normal CFTR messenger RNA (mRNA) in different org...

Objective: To determine the clinical profile of pregnant women with COVID-19 who hospitalized in a referral hospital.Methods: This was descriptive study conducted on were at Regional Hospital Bau-Bau and Bahteramas Southeast Sulawesi from May to July 2020. The confirmation based RT-PCR. Data including characteristics, profile, laboratory test, imaging, management, outcomes.Results: There 41 no ...

Cardiotocography is a series of inspections to determine the health fetus in pregnancy. The inspection process carried out by recording baby's heart rate information whether healthy condition or contrarily. In addition, uterine contractions are also used fetus. Fetal classified into 3 conditions namely normal, suspect, and pathological. This paper was performed compare classification algorithm ...

Childbirth is a unique experience for woman’s life and this reason, it necessary to ensure the right conditions have positive childbirth experience. Thus, World Health Organization has developed recommendations aimed at promoting normal better care of mother fetus without unnecessary interventions. This study presents questionnaire that measures quality intrapartum according WHO The was constru...

A family is described in which the mother, her two live offspring, and a therapeutically aborted fetus each had a ring 14 chromosomes. The two children were mentally retarded and the mother's intelligence was at the lower end of the normal range. In addition, the mother had two spontaneous abortions, one of which was shown to be chromosomally normal.

Intrauterine death of one fetus after the second trimester in a twin pregnancy, with continuation of the pregnancy is a rare complication. The risks of morbidity and mortality for the surviving fetus are high. A 32-year-old woman was admitted to the antenatal ward at 27 weeks gestation because of intrauterine death of one twin. During the first 24 h after the death of one twin, Doppler ultrasou...

In a previous report, it was suggested that intrauterine crowding impaired fetal erythropoiesis and that fetal erythropoiesis was accelerated in Meishan pigs during early pregnancy. Because these conclusions were based on limited numbers of observations, the present experiment was undertaken to provide a more extensive investigation of these phenomena. Intact white crossbred gilts, unilaterally...

A 19 week female fetus is described with a de novo X;1 reciprocal balanced translocation, with the breakpoint on the X chromosome at Xp11.4, and eye pathology consistent with the early stages of Norrie disease. The fetus seems to be an example of a female manifesting an X linked recessive disease, and it was shown that the normal X chromosome was completely inactivated in all cells examined. No...

Fetal acardia is a rare abnormality of multiple pregnancies, which is lethal for the affected fetus and can cause death in 50% of normal co-twins. Antenatal recognition with early ultrasound is essential to institute a prospective management to improve the outcome. Our communication outline the difficulties which may be encountered in ultrasound diagnosis. In particular the problem of distingui...

Intrahepatic cholestasis of pregnancy (ICP) is the pregnancy induced liver disorder causing intense itching of palm, sole or even whole body especially in the evening at late second and third trimester. This disease is categorized into mild and severe ICP according to raised level of LFT including serum level of bile acid and cholic acid. ICP has less morbidity to mother but significant risk to...