OBJECTIVE To determine the accuracy of telomerase activity in predicting a higher risk for breast cancer. STUDY DESIGN A quantitative systematic review was performed. Studies that detected telomerase activities in breast tissue were included. RESULTS Twenty-five primary studies were analyzed, which included 2395 breast lesions. The proportion of breast cancer was 60.8%. Eighty-two percent (...

Young patients with dense breasts have a relatively low-positive biopsy rate for breast cancer (∼1 in 7). South Korean women have higher breast density than Westerners. We investigated the benefit of using a functional and metabolic imaging technique, diffuse optical spectroscopic imaging (DOSI), to help the standard of care imaging tools to distinguish benign from malignant lesions in premenop...

congenital vascular lesions occur most often in children. parents of these children take them to maxillofacial surgeons directly or during the treatment of other complications such as infection or jaw bone disorders. various terms now used are unable to describe the pathogenesis and mechanism of the effect of vascular lesions on growth and development of facial bone.  term of hemangioma is used...

Normal human breast tissue consists of epithelial and nonepithelial cells with different molecular profiles and differentiation grades. This molecular heterogeneity is known to yield abnormal clones that may contribute to the development of breast carcinomas. Stem cells that are found in developing and mature breast tissue are either positive or negative for cytokeratin 19 depending on their su...

Purified collagenase which attacks only native collagen and gelatin was injected intravenously into the normal and DCA hypertensive rats to determine whether damage in collagenous tissue of the vascular wall would result in diffuse necrotizing lesions of the vessels. In the normal rats subclinical edema, proteinuria, and mild degenerative lesions in the small arteries and arterioles were produc...

There are several lasers available for office-based or suspension microlaryngoscopy laser procedures in the treatment of laryngeal diseases. Each has advantages and disadvantages given depth penetration per unit power, absorption water, spectral characteristics, mode delivery, safety, cost. It is important to note that while proper selection indication based on a wavelength critical, equal impo...

In the past decades, regenerative medicine applied on skin lesions has been a field of constant improvement for both human and veterinary medicine. The process healing cutaneous wound injuries implicates well-organized cascade molecular biological processes. However, sometimes normal fails can result in chronic lesion. addition, wounds are considered an increasing clinical impairment, due to pr...

Some types of multiwalled carbon nanotube (MWCNT) are similar to asbestos in length and diameter. When these fibers introduced into the respiratory tract, MWCNTs can induce pulmonary lesions including inflammation, fibrosis, hyperplasia. By using an intrapulmonary spraying method, we demonstrate that MWCNT causes lung cancer a 2-year experimental protocol (Suzui et al., 2016). In samples 5 hist...

INTRODUCTION: Tuberous sclerosis complex (TSC) is a rare, multi-system genetic disease that, as a result of dominant mutations of TSC1 and TSC2 genes, causes tumors/lesions to grow in various organs. In the central nervous system, TSC is predominantly characterized by cortical/subcortical tubers which are responsible for the seizures (90%) and mild to severe developmental delays found in TSC [1...