نتایج جستجو برای: nortriptyline
تعداد نتایج: 436 فیلتر نتایج به سال:
Polymorphisms in CYP2D6 and CYP2C19 affect the efficacy and safety of tricyclics, with some drugs being affected by CYP2D6 only, and others by both polymorphic enzymes. Amitriptyline, clomipramine, doxepin, imipramine, and trimipramine are demethylated by CYP2C19 to pharmacologically active metabolites. These drugs and their metabolites, along with desipramine and nortriptyline, undergo hydroxy...
Psychiatric drugs are among the leading medications prescribed for humans, with their presence in aquatic environments raising concerns relating to potentially harmful effects on non-target organisms. Nortriptyline (NTP) is a selective serotonin-norepinephrine reuptake inhibitor antidepressant, widely used clinics and found environmental water matrices. In this study, we evaluated toxic of NTP ...
Specific interventions included in the review Studies of RIMAs, i.e. MOC (18 to 600 mg) or BRO (93.1 to 150 mg/day) versus either placebo or another standard tricyclic antidepressant, selective serotonin re-uptake inhibitor (SSRI) or other class of antidepressant, were included. The active comparison groups included: diazepam, tranylcypromine, mianserin, isocarboxide, imipramine, amitriptyline,...
Anti-inflammatory activity has been reported for a few of antidepressant drugs and in contrary sertraline has potentiated inflammation. In this study, anti-inflammatory effect of a collection of antidepressant drugs belonging to different classes was evaluated to help a rational selection of these drugs in disease conditions such as association of depression or anxiety with inflammatory d...
objective: to manage a treatment resistant depression, clinicians may add a second medicationto the first antidepressant drug. the aim of the current research was to study the outcome of augmentation of citalopram with nortryptiline or triiodothyronine in a randomized clinical trial. methods: we selected 48 adult outpatients with a diagnosis of non-psychoticmajor depressive disorder who had not...
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