Claus T. Fuchs and Gerhard Spiteller Institut für Organische Chemie I, Universität Bayreuth, Universitätsstr. 30, D-95440 Bayreuth, Germany Z. Naturforsch. 53c, 799-805 (1998); received February 20/April 16, 1998 Taphrina pruni, Plums, Catechins, Caffeoyl-D-quinic Acids, Photometric Determination Plums (Prunus domestica) affected by the fungus Taphrina pruni and healthy ones were harvested in i...

A phytochemical study of dart and arrow poison from the Matis tribe led to the identification of D-(-)-quinic acid, L-malic acid, ethyldimethylamine, magnoflorine, and five new bisbenzyltetrahydroisoquinoline alkaloids (BBIQAs), 1-5. D-Tubocurarine could not be identified among these products. BBIQA (3) contains a unique linkage at C-8 and C-11'. All structures were characterized by a combinati...

Copper ions are essential for many biological processes. However, high concentrations of copper can be detrimental to the cell or organism. A novel naphthalimide derivative bearing a monoboronic acid group (BNP) was investigated as a Cu(2+) selective fluorescent sensor in living cells. This derivative is one of the rare examples of reversible fluorescent chemosensors for Cu(2+) which uses a bor...

Cancer detection in early stage using a powerful and noninvasive tool is of high global interest. In this experiment, a small-molecular-weight glucose based derivative of Gd3+-1-(4-isothiocyanatobenzyl) diethylene tri amine penta acetic acid (Gd3+-p-SCN-Bn‐DTPA‐DG) as a novel potential MR imaging contrast agents was synthesized. Gd3+-p-SCN-Bn‐DTPA‐DG was synthesized with reacting of Glucosamine...

The neuroprotective effect of flower and fruit parts Capparis ovataDesf. var. palaestinaZoh. plant was investigated in H2O2-induced cytotoxicity SH-SY5Y cells. cells were treated with H2O2alone or pretreated (COMFL) extract (COMFR) C. ovatavar. palaestina. MTT, xCELLigence, qualitative quantitative determination phytochemical constituents the extracts by LC-MS/MS methods employed. COMFL COMFR h...

The aim of the present study was to investigate the effects of an oleanolic acid derivative, a novel antitumor drug, on the growth of SMMC-7721 human hepatocellular carcinoma cells and the underlying mechanism. An MTT assay was performed to determine the cytotoxicity of the oleanolic acid derivative. Cell membrane integrity was assessed using fluorescence microscopy to assess the uptake of anne...

The chemical study of Laennecia schiedeana afforded three sterols, five diterpenes, five flavonoids, three caffeoyl derivatives of quinic acid, and two triterpenes. Evaluation of the cytotoxic activity of the extracts and isolated metabolites showed that 15-methoxy-16-oxo-15,16H-strictic acid was the most active compound [(15.05 +/- 2.2) microg/mL against U-251 cells]. In antibacterial assays t...

Background and objectives: Plants of genus Clinopodium have been used in different cultures as traditional medicines.Due to theimportance of medicinal properties of the genus Clinopodium, C. umbrosum was selected for phytochemical analysis along with evaluation of its antioxidant property. Methods: The aerial parts of C. umbrosum<...

A promising approach for treating diabetes mellitus (DM) is to decrease postprandial hyperglycaemia by suppressing carbohydrate digestion using α-glucosidase inhibitors. Pluchea indica leaf extracts possess inhibitory activity against intestinal maltase. Enzyme assay-guided fractionation by chromatography yielded five active caffeoylquinic acid derivatives (1-5). Their structures were elucidate...

A novel nonlinear fractional order sliding mode controller is proposed to control the chaotic atomic force microscope system in presence of uncertainties and disturbances. In the design of the suggested fractional order controller, conformable fractional order derivative is applied. The stability of the scheme is proved by means of the Lyapunov theory based on conformable fractional order deriv...