In this thesis, we use finite difference operators with the Summation-By-Parts property (SBP) and a weak boundary treatment, known as Simultaneous Approximation Terms (SAT), to construct high-order accurate numerical schemes. The SBP property and the SAT’s makes the schemes provably stable. The numerical procedure is general, and can be applied to most problems, but we focus on hyperbolic probl...

We performed a retrospective study of 25 patients who died of severe falciparum malaria in Thailand and Vietnam using electron microscopy. The aims of the study were: to determine if there was any significant association between parasitized red blood cells (PRBC) sequestered in liver and spleen and particular pre-mortem clinical complications, and to compare the degree of parasite load between ...