نتایج جستجو برای: nuclear antibody
تعداد نتایج: 398706 فیلتر نتایج به سال:
Background: Blocking the PD1-PD-L1 interaction has been shown to stimulate anti-tumour responses. Although antibody-based drugs targeting either PD-1 or PD-L1 are approved, small molecule inhibitors of currently in development. A subset these induce loss cell surface a time- and concentration-dependent manner. INCB090244 is that previously bind disrupt PD-L1/PD-1 interaction. Materials Methods:...
BACKGROUND Recent reports on Propionibacterium acnes (P. acnes) suggest that this bacterium is prevalent in the prostate, is associated with acute and chronic prostatic inflammation, and might have a role in prostate carcinogenesis. METHODS To evaluate the pathogenic role of this indigenous bacterium, we screened for the bacterium in radical prostatectomy specimens using enzyme immunohistoche...
Immunoglobulin G (IgG) antibodies to Epstein-Barr virus (EBV) nuclear antigens 2 and 1 (EBNA-2 and EBNA-1, respectively) were studied using sera from healthy individuals of a population with a high incidence of asymptomatic primary EBV infections during infancy or childhood in Japan. Two CHO-K1 cell lines expressing EBNA-2 and EBNA-1 were used for anticomplement and indirect immunofluorescence ...
breast cancer radioimmunoscintigraphy targeting her2/neu expression is a growing fieldof work in nuclear medicine research. in this study, trastuzumab was successively labeledwith [67ga] gacl3 after conjugation with dota-nhs-ester.the conjugates were purified by molecular filtration, the average number ofdota conjugated per mab was calculated and total concentration was determined byspectrophot...
Background: Though the incidence of colorectal carcinoma (CRC) is relatively uncommon in Nigeria, compared to the developed countries, recent studies indicate an increasing trend. Our patients often present at an earlier age, which has important implications for the pathogenesis in Nigeria. MLH1, MSH2, MSH6, PMS2 are the commonly mutated MMR genes in descending order of frequency, with PMS1 and...
in the first chapter we study the necessary background of structure of commutators of operators and show what the commutator of two operators on a separable hilbert space looks like. in the second chapter we study basic property of jb and jb-algebras, jc and jc-algebras. the purpose of this chapter is to describe derivations of reversible jc-algebras in term of derivations of b (h) which are we...
background: celiac disease is one of the malabsorption syndromes leads to growth and development retardation in children. there is no test lonely can definitely diagnose celiac; however, the collection of clinical findings, serologic tests, intestinal biopsy, and response to treatment may diagnose it. although diagnostic value is variable in different studies, they are used a non-invasive and a...
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