CHARGE syndrome is a genetic disorder characterized by choanal atresia, coloboma of the eye, and ear and cranial nerve abnormalities. We report a child with CHARGE syndrome and obstructive sleep apnea. We highlight difficulties in discerning obstructive sleep apnea-related symptoms from typical features of CHARGE syndrome. Treatment options are discussed with regard to our patient. Tonsillectom...

I. POLICY Pharyngometry and rhinometry are considered investigational as techniques for screening, diagnosis, or treatment planning in persons with known or suspected obstructive sleep apnea (OSA) and for all other indications. There is insufficient evidence to support a conclusion concerning the health outcomes or benefits associated with these procedures Cross-references MP 2.045 Diagnosis an...

This paper, which has been reviewed and approved by the Board of Directors of the American Sleep Disorders Association, provides the background for the Standards of Practice Committee's parameters for the practice of sleep medicine in North America. The intent of this paper is to provide an overview of the surgical treatment of obstructive sleep apnea syndrome, to provide the basis for the Amer...

STUDY OBJECTIVE Sleep-disordered breathing (SDB) is a prevalent condition in children and is associated with increased cardiovascular morbidity. Circulating levels of C-reactive protein (CRP), a proinflammatory protein, are associated with increased risk for atherosclerosis. Plasma CRP levels in snoring children have yielded conflicting results, such that it remains unclear whether OSA is mecha...

snoring and obstructive sleep apnea: a review. Sleep 2006; 29: 244–262. 3 Tsuiki S, Kobayashi M, Namba K, et al. Optimal positive airway pressure predicts oral appliance treatment response to sleep apnoea. Eur Respir J 2010; 35: 1098–1105. 4 Isono S. Upper airway muscle function during sleep. In: Loughlin GM, Varroll JL, Marcus CI, eds. Sleep and Breathing in Children. New York, Marcel Dekker, ...

BACKGROUND A link between obstructive sleep apnea and cancer development or progression has been suggested, possibly through chronic hypoxemia, but supporting evidence is limited. We examined the association between the severity of obstructive sleep apnea and prevalent and incident cancer, controlling for known risk factors for cancer development. METHODS We included all adults referred with ...

OBJECTIVE To investigate the effect of obstructive sleep apnea and continuous positive airway pressure treatment on serum butyrylcholinesterase activity and ischemia-modified albumin levels. METHODS Thirty-two patients with obstructive sleep apnea and 30 age- and sex-matched controls were enrolled and underwent a diagnostic polysomnogram. The serum butyrylcholinesterase activity, ischemia-mod...

Introduction: Obstructive sleep apnea (OSA) is a highly prevalent sleep-disordered breathing (SDB).   Case Report: Two 53- and 51-year-old male cases with daytime sleepiness and opium abuse and severe sleep apnea and long respiratory events duration (200 and 275 seconds respectively) noted in polysomnography were reported at Ebn-e-Sina and Razavi hospita...

Obstructive sleep apnea causes intermittent elevation of systemic blood pressure (BP) during sleep. To determine whether obstructive apnea in children has a tonic effect on diurnal BP, 24-hour ambulatory blood pressure was obtained from 60 children with mean age of 10.8 +/- 3.5 years. Thirty-nine children had obstructive apnea and 21 had primary snoring. Children with obstructive apnea had sign...

STUDY OBJECTIVES Current actigraphic algorithms are relatively less accurate in detecting sleep and wake in sleep apnea patients than in people without sleep apnea. In the current study, we attempted to validate a novel automatic algorithm, which was developed for actigraphic studies in normal subjects and patients with obstructive sleep apnea by comparing it on an epoch-by-epoch basis to stand...