dorzolamide ophthalmic drop is one of the most common glaucoma medications but it has a short residence time in the eye. the aim of this study is to develop ocular dorzolamide hcl nanoliposomes (drz – nanoliposomes) and to evaluate their potential use for the treatment of ocular hypertension. nanoliposomes were prepared using reverse-phase evaporation vesicle (rev) and thin layer hydration (tlh...

purpose: to determine the prevalence of intraocular injuries in patients with blow-out fracture and also to evaluate the etiologic mechanism of orbital blow-out fractures methods: this study is a consecutive case series analysis of 116 patients with orbital blow-out fractures. the patients were visited by an ophthalmologist within 24 hours of trauma. results: ninety-one men and twenty-five wome...

we are describing a new surgical approach in the management of advanced ocular surface cicatrization through a single procedure conjunctival-limbal-corneal allograft in which the external eye is resurfaced it involves a lamellar corneolimbal keratoplasty, 360° limbal stem cell transfer (on a “bipedicle” conjunctival-corneal carrier), and conjunctival tissue transplantation - all in a single con...

BACKGROUND The purpose of this study was to investigate the correlation between ocular perfusion pressure and ocular pulse amplitude in glaucoma, ocular hypertension, and normal eyes. METHODS Ninety eyes from 90 patients were included. Thirty patients had been recently diagnosed with glaucoma and had no previous history of treatment for ocular hypotension, 30 had elevated intraocular pressure...

Background: During the COVID-19 pandemic, the presence of ocular symptoms was common in COVID-19 patients, which can cause secondary complications in the treatment of ocular diseases. On the other hand, obesity can cause secondary symptoms in infectious diseases by impairing the function of the immune system, which indicates the relationship between involvement of different tissues and dysfunct...

results this cross-sectional study included 92 patients (47 male and 45 female) with mean age of 32.1 ± 13.16 years (ranging from nine to 61 years of age). mean duration of vitiligo was 10.84 ± 10.17 years. the most common distribution of the lesions was on the upper limbs (60.8%) and the least was on the genital region (10.8%). positive family history was found in 26 (28.3%) patients. diabetes...

purpose : to determine the relationship between refractive errors and ocular components values in carpet weavers methods : refractive errors and ocular components values were investigated on carpet weavers at mashhad city in iran . after selection of samples, the individuals who had ophthalmic and systemic disease effective on the refractive errors were excluded from the study. refractive error...

purpose: to evaluate the effect of childhood corneal opacity on the anteroposterior length of the globe in adulthood. methods: twenty-three patients with significant unilateral corneal opacity which had developed before the age of 6 years and the normal fellow eyes (controls) were evaluated. a comprehensive ocular examination including measurement of anterioposterior length and anterior chamber...

purpose: to determine the distribution of oculomotor, abducens, and trochlear nerve palsies in diabetic patients with ocular nerve palsy. methods: this study was performed on all diabetic patients who referred to ophthalmology and neurology clinics at yazd medical science university because of ocular palsy from march 2004 to october 2005. signs and symptoms of the disorder were evaluated. resul...

BACKGROUND AND PURPOSE Ocular pulse amplitude, the amplitude of the ocular pneumoplethysmographic waveform, is altered in several ophthalmologic diseases that disturb ocular blood flow, implying that ocular pulse amplitude may provide an estimate of ocular blood flow. Because ocular blood flow currently cannot be quantified in humans, two experiments were undertaken to evaluate the association ...