Oculomotor abnormalities are rarely noted in thalamic strokes. We describe isolated right pseudoabducens palsy in a young patient with acute left thalamic infarction revealed by diffusion-weighted magnetic resonance imaging. The patient's horizontal diplopia and oculomotor palsy resolved within 3days. This case supports the hypothesis that a lesion can cause isolated esotropia by interrupting d...

friedreich’s ataxia (frda) is a rare autosomal recessive spinocerebellar ataxia which in the majority of cases is associated with a gaa-trinucleotide repeat expansion in the first intron of frataxin gene located on chromosome 9. the clinical features include progressive gait and limb ataxia, cerebellar dysarthria, neuropathy, optic atrophy, and loss of vibration and proprioception. ataxia with ...

BACKGROUND Ataxia with oculomotor apraxia type 2 (AOA2) is an autosomal recessive disease caused by SETX mutations in 9q34 resulting in cerebellar ataxia in association with peripheral neuropathy, cerebellar atrophy on imaging, an elevated alpha-fetoprotein (AFP) serum level, and occasional oculomotor apraxia. OBJECTIVE To describe the clinical and molecular findings of 7 patients with a clin...

OBJECTIVE To further assess oculomotor control of patients with Parkinson disease (PD) during fixation and with movement. DESIGN Case-control study. SETTING A Parkinson disease research, education, and clinical center. PATIENTS One hundred twelve patients with PD, including 18 de novo untreated patients, and 60 age-matched controls. INTERVENTION Modern, precise eye tracking technology was...

To cite: Liao B, KamiyaMatsuoka C. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014207749 DESCRIPTION A 44-year-old man with hyperlipidaemia and chronic hepatitis C infection presented with a 48 h history of diplopia and occipital headaches. On neurological examination, he was alert and afebrile. There was right oculomotor palsy consisting of right medial rect...

Essential tremor (ET) is the most prevalent movement disorder, characterized mainly by an action tremor of the arms. Only a few studies published as yet have assessed oculomotor abnormalities in ET and their results are unequivocal. The aim of this study was to assess the oculomotor abnormalities in ET patients compared with the control group and to find the relationship between oculomotor abno...

The objective of this study was to explore whether there was a functional link between trigeminal proprioception and the oculomotor system mediated through jaw muscle afferents. Electromyography (EMG) was undertaken of the levator palpebrae (LP) and superior rectus (SR), and Fos expression was detected in the brainstem following consecutive down-stretching of the lower jaw at 2-4 Hz in rats. Re...

The ability to pursue moving objects with the eyes is vital to humans. However, it remains unclear how the brain differentiates visual object motion, smooth pursuit eye movements (SPEM), and eye movement-induced relative motion on the retina and where visual-to-oculomotor transformation takes place. To characterize functional differences of SPEM-processing cortical areas, we simultaneously meas...

In recent years two of us have investigated the neural structure of the visual fixation reflex in the cat (Dreher et al. 1965, Dreher and i e r nicki 1969ab). In these studies we were interested in the effects of ablfation of cortical oculomotor areas. However, available data in the localination of these areas are not adequate. In anesthetized cats relatively small cortical ocu~lomotor areas we...