BACKGROUND Previous reports have indicated an association between Barrett's metaplasia or adenocarcinoma of the oesophagus and colonic neoplasia, but the findings have been inconsistent. If true, such an association suggests common causal mechanisms. AIMS To test the hypothesis of an association between Barrett's metaplasia or adenocarcinoma of the oesophagus and colonic neoplasia. METHODS ...

OBJECTIVES Later weekday of surgery for oesophageal cancer seems to increase 5-year mortality, but the mechanisms are unclear. We hypothesised that early postoperative reoperations and mortality might explain this association, since reoperation after oesophagectomy decreases long-term prognosis, and later weekday of elective surgery increases 30-day mortality. DESIGN This was a population-bas...

BACKGROUND Although pernicious anaemia is an established risk factor for stomach cancer, data by anatomical subsite are not available. Moreover, a previous suggestion of a link to increased risk of oesophageal cancer needs further exploration. METHODS We followed 21 265 patients hospitalised for pernicious anaemia in Sweden from 1965 to 1999 for an average of 7.1 years. Standardised incidence...

This study aimed to examine whether changes in the illness perceptions of oesophageal cancer survivors explain changes in their levels of psychological distress relative to demographic and biomedical variables and coping strategies. Oesophageal cancer survivors completed the Illness Perception Questionnaire - Revised, the Cancer Coping Questionnaire and the Hospital Anxiety and Depression Scale...

INTRODUCTION Oesophageal carcinomas represent 3% of all cancers in the UK accounting for 7650 new cases per annum. Oesophageal cancer may be associated with swallowing abnormalities, localised mass pressure effects, lymphatic or distant metastatic spread. CASE PRESENTATION We report a 50-year-old man who presented with a painful, enlarging, solid, fixed lesion adjacent to the left buttock wit...

Abstract Background Patients with oesophageal or gastro-oesophageal junction (GOJ) cancer that fail to respond chemoradiotherapy have a poor clinical prognosis. Recent trials investigated the use of immune checkpoint inhibitors in these patients. The programmed cell death protein 1 (PD-1) emerged as exciting therapeutic options other solid tumors, such non-small lung cancer, renal carcinoma and...

Synchronous cancers of the oesophagus and stomach diagnosed in a patient showing pronounced leucocytosis were examined for production of granulocyte colony stimulating factor (G-CSF) and expression of G-CSF receptor. Whereas enzyme immunoassay of tissue extracts showed that the oesophageal carcinoma produced G-CSF, the gastric cancer did not. However, the gastric tumour showed G-CSF receptor ex...

BACKGROUND Observational studies have indicated that high calcium intake may prevent colorectal cancer, but as for randomized trials the results are inconclusive. Meanwhile, limited data on the link between serum calcium and cancer risk is available. We investigated the relation between serum calcium and risk of different gastrointestinal cancers in a prospective study. METHODS A cohort based...

Sudden onset haematemesis occurred in a 52-year old male with oesophageal cancer. Computed tomography showed an aorto-oesophageal fistula with contrast extravasation from the aorta. Thoracic endovascular aortic repair with stent graft was done. The haematemesis stopped postoperatively, but follow-up images (Fig. 1) showed persistent contrast extravasation. The patient died of another episode of...

Oesophageal cancer is the eighth most common cancer worldwide, and the sixth most common cause of death from cancer. From a worldwide perspective, one of the most striking features of oesophageal cancer is the extreme geographic variation in incidence. At a global level, a 20-fold difference is seen in offi cial statistics between high-risk and low risk areas (1). This difference becomes even m...