A significant and increasing number of chronic kidney disease (CKD) patients are treated with online hemodiafiltration (OL-HDF), even in the absence of more conclusive survival data. OL-HDF affords several clinical benefits including control of anemia of CKD, a common affliction in dialysis patients. In efforts to understand the underlying mechanisms that contribute to the purported benefits of...

In the premature infant, hypoxic-ischemic damage to the cerebral white matter [periventricular leukomalacia (PVL)] is a common and leading cause of brain injury that often results in chronic neurologic disability from cerebral palsy. The cellular basis for the propensity of white matter injury to occur in the developing brain and the greater resistance of the adult white matter to similar injur...

The possibility that the serum concentrations of various cholesterol precursors may reflect the activity of the hepatic HMG-CoA reductase was investigated in humans under different conditions. The serum levels of squalene, free and esterified lanosterol, (4 alpha, 4 beta, 14 alpha-trimethyl-5 alpha-cholest-8, 24-dien-3 beta-ol), two dimethylsterols (4 alpha, 4 beta-dimethyl-5 beta-cholest-8-en-...

BACKGROUND Oleuropein (OL) is a well-known anti-oxidative agent and is shown to reduce the hypoxia-inducible factor 1 α (HIF1α) protein expression after radiation. The current study investigated the effects of OL on radiation response in nasopharyngeal carcinoma (NPC). METHODS Colony formation assay was performed to compare the radiation response in vitro. Xenograft mouse model was used to st...

Progesterone was converted to 5alpha-pregnane-3alpha-ol-20-one, delta4-pregnene-20alpha-ol-3-one, delta4-pregnene-14alpha-ol-3,20-dione, delta4-pregnene-7beta,14alpha-diol-3,20-dione, and delta4-pregnene-6beta,11alpha-diol-3,20-dione by cell cultures of Lycopersicon esculentum. Cell cultures of Capsicum frutescens (green) metabolized progesterone to delta4-pregnene-20alpha-ol-3-one in very high...

The dehydrogenation reaction of cholest-7-en-3P-ol (I) to cholesta-5,7-diem3/3-ol (II) in the presence of NADH was studied in rat liver microsomes and in microsomal acetone powder preparations, using [3Lu-“Hlcholest-‘7-en-3fi-o1. It was found that the reaction was inhibited by menadione, adenosine diphosphate, potassium ferricyanide, and cytochrome c while p-cresol had no effect. These results ...

a au a a y y , d tics and Molecular Cardiology y y , : d d di i i, P P Ph h h.D D D. ti ti tics cs a and nd nd d d M M M M Mol ol ol l lec ecul ul ular ar C C Car ardi di di di diol ol ol l log ogy y Abstract Background—The present study addressed the hypothesis that the activity of dipeptidyl

Abstract Dysregulation of the cell cycle is an important factor in a potentially malignant oral disorder. There have not been many studies on role regulator p27 non-homogenous leukoplakia. The aim our study was to characterise protein homogenous and leukoplakias (OL), comparison with healthy mucosa squamous carcinoma tissues. current included 25 patients OL, 15 cases carcinoma, samples mucosa, ...

ketab-ol-ein, which was written by ahmad farahidi, is one of the oldest dictionaries that exist today. in the preliminary discussion we mentioned that, although historical sources show that the work of ibn abbas looks like a dictionary, it is becoming accepted that ketab-ol-ein is the first dictionary. the article starts with explanations about the life and work of khalilibn ahmad. we have also...

this experiment was conducted to investigate the effects of olive leaf (ol) on immune response and some blood metabolites of broiler chickens. a total of 400 one-day-old broiler chicks (male and female) were randomly assigned to 5 experimental treatments with 4 replicates of 20 birds each. birds of different treatments were given diets containing 0, 0.25, 0.5, 0.75 and 1% ol powder from 14 to 4...