background: the secretion of thyroxin (t4) as the main hormone of thyroid gland is regulated by androgens. the present study aimed to evaluate the effect of testosterone and finasteride administration and castration on serum levels of t4 and to show the effect of this regulation on total body weight, weight of testis, and the weight of prostate. methods: male adult rats (n = 32) were divided in...

background: ritalin has high tendency to be abused. it has been the main indication to control attention deficit hyperactivity disorder. the college students may seek for it to improve their memory, decrease the need for sleep (especially during exams), which at least partially, can be related to serotonergic system. therefore, it seems worthy to evaluate the effect of ritalin intake on mature ...

background toxoplasma gondii is a unicellular apicomplex organism, belonging to the toxoplasma genus. the parasite infects humans, as well as mammalians and different species of birds, and it can be propagated in a wide range of host cells. there have been no appropriate molecular or serological studies carried out previously in iran on the prevalence of toxoplasma gondii in rodents. objectives...

background: oral vanadyl sulfate (vanadium) induces normoglycemia, proliferates beta cells and prevents pancreatic islet atrophy in streptozotocin-induced diabetic rats. soteriological method is used to quantitate the proliferative effects of vanadium on beta-cell numbers and islet volumes of normal and diabetic rats. methods: adult male sprague-dawley rats were made diabetic with intravenous s...

objective: curcumin is a major constituent of turmeric and influences many functions of the brain. in the present study, we investigated the effect of curcumin on yawning induced by apomorphine in rats. materials and methods: curcumin administered orallyfor 10 consecutive days. yawning was induced by subcutaneous (s.c.) injection of apomorphine (a dopamine receptor agonist) and the number of ya...

objective: the present study was hypothesized to investigate the beneficial effects of fresh, aged, and cooked garlic extracts on blood glucose and memory of diabetic rats induced by streptozocine (stz). material and methods: diabetes was induced by an intraperitoneal injection of stz (60 mg/kg body weight). an oral dose of 1000 mg/kg of each garlic extract was given daily for 4 weeks after dia...

objectives:crocin is one of constituents of saffron and has antioxidant property. zinc chloride is one of the common compounds of zinc with antioxidant activity. the present study was aimed to investigate separate and combined treatment effects of crocin and zinc chloride on blood levels of zinc and metabolic and oxidative parameters in diabetic rats. materials and methods:diabetes was induced ...

background: hyperprolactinemia is a common side effect of antipsychotic drugs that requires further investigation. the current study was designed to evaluate dose-dependent effect of chlorpromazine (cpz) on hormonal changes and uterine horn histological structure in rats. moreover, the mammary glands were analyzed to show hyperprolactinemia-induced histological changes. methods: albino wistar r...