The issue of fertility preservation in patients with cervical cancer is getting more and common considering the improved effectiveness early diagnosis treatment cancer. There a number evidence-based tactics available to diagnosed These have been proved effective include methods such as ovarian transposition; oocyte, embryo tissue cryopreservation. Nonetheless, there are no existing medical algo...

Background: Age is an important factor in the success of infertility treatment. Upper limit of the age that people can get into infertility treatments vary in different countries. This study investigated the relationship between age and BMI with laboratory parameters in women undergoing ART and oocytes extracted from the ICSI procedure in Omid Infertility Center in Babol. Materials and Methods:...

BACKGROUND There is preliminary evidence to suggest an impact of stress on chances of achieving a pregnancy with in-vitro fertilization (IVF). The majority of the available research has focused on stress related to infertility and going through IVF-treatment, and it is still unclear whether non-fertility-related, naturally occurring stressors may influence IVF pregnancy chances. Our aim was to ...

Background: Heat shock may affect different aspects of oocyte maturation and its subsequent development to the blastocyst stage. A series of in vitro experiments was performed to determine whether physiologically heat shock (41°C) disrupts the progression of the ovine oocytes through meiosis, activation and blastocyst formation. Materials and Methods: The cumulus-oocyte complexes (COCs) were as...

current protocols for cancer treatment could lead to the failure of ovarian function and subsequent infertility in women. therefore, utilizing ways to preserve fertility in these individuals seem to be essential. in this review, the full-text of articles which were accessible and had been published during 1976 to 2009 about different methods of female fertility preservation were collected and s...

Coordinated regulation of oocyte and ovarian follicular development is essential for fertility. In particular, the progression of meiosis, a germ cell-specific cell division that reduces the number of chromosomes from diploid to haploid, must be arrested until just before ovulation. Follicular somatic cells are well-known to impose this arrest, which is essential for oocyte-follicle development...

Fertilization involves cell-cell fusion of a sperm with the oocyte. This fusion restores the diploid genome, activates the oocyte, and initiates embryonic development. The identification of proteins mediating the fusion of sperm with oocyte plasma membrane (oolemma) is important to a deeper knowledge of fertilization. Defects in sperm-oocyte fusion may account for some form of human infertility...

OBJECTIVE During stimulated IVF cycles, up to 15% of oocytes are recovered as immature. The purpose of this study was to investigate the trend of oocyte maturity in repeated ovarian stimulation for IVF. METHODS One hundred forty-eight patients were selected who underwent two consecutive IVF cycles using same stimulation protocol during 2008 to 2010. Ovarian stimulation was performed with FSH ...

BACKGROUND Mammalian oocyte meiotic maturation involves a number of important processes, including spindle assembly and migration, cortical reorganization and polar body extrusion. Numerous proteins contribute to these processes, but it is unknown whether MKlp2 (mitotic kinesin-like protein 2; also called KIF20A), a microtubule-associated protein that regulates cytokinesis during mitosis, is in...

Oogenesis in Drosophila is a useful model for studying cell differentiation. We have analyzed the role of the egh gene in these processes with the aid of a newly isolated viable but female sterile allele. This mutation results in diverse variable defects in oogenesis. The most frequent defect being follicles that have either more or less than the normal number of 16 germ cells. This is caused b...